Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jun 27, 2026

Full-Field Optical Coherence Microscopy for Histology-Like Analysis of Stromal Features in Corneal Grafts
07:51

Full-Field Optical Coherence Microscopy for Histology-Like Analysis of Stromal Features in Corneal Grafts

Published on: October 21, 2022

Direct corneal elevation measurements using multiple delay en face optical coherence tomography.

Lucian Plesea1, Adrian Gh Podoleanu

  • 1University of Kent, Applied Optics Group, Canterbury, United Kingdom. lp25@kent.ac.uk

Journal of Biomedical Optics
|November 22, 2008
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Enhanced resolution optoacoustic microscopy using a picosecond high repetition rate Q-switched microchip laser.

Journal of biomedical optics·2022
Same author

Quantitative assessment of rat bone regeneration using complex master-slave optical coherence tomography.

Quantitative imaging in medicine and surgery·2019
Same author

Noninvasive Quantitative Evaluation of the Dentin Layer during Dental Procedures Using Optical Coherence Tomography.

Computational and mathematical methods in medicine·2015
Same author

Demonstration of tolerance to dispersion of master/slave interferometry.

Optics express·2015
Same author

Dual-mode-locking mechanism for an akinetic dispersive ring cavity swept source.

Optics letters·2015
Same author

Surface imaging of metallic material fractures using optical coherence tomography.

Applied optics·2014

A novel optical coherence tomography (OCT) method directly measures anterior cornea surface elevation using a single en face OCT image. This technique provides precise 3D corneal topography, enhancing ophthalmic diagnostics.

Area of Science:

  • Ophthalmology
  • Biomedical Optics
  • Medical Imaging

Background:

  • Optical coherence tomography (OCT) is a standard imaging technique in ophthalmology.
  • Accurate corneal topography is crucial for diagnosing and managing various eye conditions.

Purpose of the Study:

  • To introduce a novel corneal topography method using a single en face OCT image.
  • To enable direct measurement of anterior cornea surface elevation.
  • To generate a 3D topographic map of the anterior cornea.

Main Methods:

  • Utilized a modified OCT interferometer with a multiple delay element (MDE) in the reference arm.
  • The MDE allowed simultaneous acquisition of data from multiple axial positions into a single en face OCT frame.
  • Corneal topography was generated from 3D coordinates derived from nonoverlapping circular contours in the en face OCT images, with calibration performed using a metallic sphere.

More Related Videos

Corneal Confocal Microscopy: A Novel Non-invasive Technique to Quantify Small Fibre Pathology in Peripheral Neuropathies
11:29

Corneal Confocal Microscopy: A Novel Non-invasive Technique to Quantify Small Fibre Pathology in Peripheral Neuropathies

Published on: January 3, 2011

Related Experiment Videos

Last Updated: Jun 27, 2026

Full-Field Optical Coherence Microscopy for Histology-Like Analysis of Stromal Features in Corneal Grafts
07:51

Full-Field Optical Coherence Microscopy for Histology-Like Analysis of Stromal Features in Corneal Grafts

Published on: October 21, 2022

Corneal Confocal Microscopy: A Novel Non-invasive Technique to Quantify Small Fibre Pathology in Peripheral Neuropathies
11:29

Corneal Confocal Microscopy: A Novel Non-invasive Technique to Quantify Small Fibre Pathology in Peripheral Neuropathies

Published on: January 3, 2011

Main Results:

  • Successfully acquired in vivo cornea topography data.
  • Demonstrated direct measurement of anterior cornea surface elevation from a single en face OCT image.
  • Generated 3D corneal surface coordinates and topographic maps.

Conclusions:

  • The novel OCT-based method offers a direct and efficient approach for anterior cornea topography.
  • This technique has the potential to improve diagnostic capabilities in ophthalmic practice.
  • The method provides accurate 3D corneal surface data from a single scan.