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Related Concept Videos

Selectins01:25

Selectins

Cell adhesion is  an essential aspect of multicellularity. While stable cell interactions usually occur between cells of the same type, transient cell interactions occur between cells of different tissue types, such as between neutrophils and endothelial cells. Selectins are one class of cell adhesion molecules (CAMs) that bind carbohydrate ligands to form transient cell adhesion. They are rod-like proteins with a long extracellular part of variable length ending with the lectin domain, which...
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Tagging and Fusion Proteins

Proteins are involved in several cellular processes and biochemical reactions. Analyzing a specific protein of interest requires it to be isolated from the other proteins in the cell. This is achieved by overexpressing the specific gene in a suitable host to produce large quantities of the target protein. A tag or label is recombined with the gene to produce a fusion protein containing the target protein and the tag. The tags on these fusion proteins can then be used for easy detection and...
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Production of Pharmaceuticals

Industrial insulin production uses genetically engineered E. coli expressing a proinsulin gene controlled by a tryptophan promoter and containing a methionine linker for later cleavage. The cells also carry ampicillin resistance for selective growth. Seed cultures are stored at −80 °C and production begins by thawing a small amount to inoculate starter cultures, which are progressively scaled to a 50,000-L bioreactor. In the bioreactor, E. coli grow in nutrient-rich media under sterile, tightly...
Integrins01:10

Integrins

Animal and protozoan cells do not have cell walls to help maintain shape and provide structural stability. Instead, these eukaryotic cells secrete a sticky mass of carbohydrates and proteins into the spaces between adjacent cells. This network of proteins and molecules is called an extracellular matrix or ECM.
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Structural Protein Function01:56

Structural Protein Function

Structural proteins are a category of proteins responsible for functions ranging from cell shape and movement to providing support to major structures such as bones, cartilage, hair, and muscles. This group includes proteins such as collagen, actin, myosin, and keratin.
Collagen, the most abundant protein in mammals, is found throughout the body. In connective tissue, such as skin, ligaments, and tendons, it provides tensile strength and elasticity.  In bones and teeth, it mineralizes to form...
Next-generation Sequencing03:00

Next-generation Sequencing

The first human genome sequencing project cost $2.7 billion and was declared complete in 2003, after 15 years of international cooperation and collaboration between several research teams and funding agencies. Today, with the advent of next-generation sequencing technologies, the cost and time of sequencing a human genome have dropped over 100 fold.
Next-Generation Sequencing Methods
Although all next-generation methods use different technologies, they all share a set of standard features.

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Related Experiment Video

Updated: Jun 27, 2026

Removal and Replacement of Endogenous Ligands from Lipid-Bound Proteins and Allergens
09:09

Removal and Replacement of Endogenous Ligands from Lipid-Bound Proteins and Allergens

Published on: February 24, 2021

Lectins: past, present and future.

Nathan Sharon1

  • 1Department of Biological Chemistry, Weizmann Institute of Science, Rehovot, Israel. nathan.sharon@weizmann.ac.il

Biochemical Society Transactions
|November 22, 2008
PubMed
Summary
This summary is machine-generated.

Plant lectins are versatile sugar-binding proteins crucial for studying cell interactions and glycoconjugates. This review explores their development, roles in cell recognition, and potential medical applications.

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A Lectin HPLC Method to Enrich Selectively-glycosylated Peptides from Complex Biological Samples
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A Lectin HPLC Method to Enrich Selectively-glycosylated Peptides from Complex Biological Samples

Published on: October 1, 2009

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Last Updated: Jun 27, 2026

Removal and Replacement of Endogenous Ligands from Lipid-Bound Proteins and Allergens
09:09

Removal and Replacement of Endogenous Ligands from Lipid-Bound Proteins and Allergens

Published on: February 24, 2021

A Lectin HPLC Method to Enrich Selectively-glycosylated Peptides from Complex Biological Samples
20:23

A Lectin HPLC Method to Enrich Selectively-glycosylated Peptides from Complex Biological Samples

Published on: October 1, 2009

Area of Science:

  • Biochemistry
  • Cell Biology
  • Immunology

Background:

  • Lectins are ubiquitous sugar-binding proteins found across all life forms.
  • They play roles in cell agglutination and recognition.
  • Plant lectins have become essential tools in biological research.

Purpose of the Study:

  • To review the development and applications of plant lectins.
  • To summarize the role of lectins in cell recognition.
  • To discuss medical applications and future research directions.

Main Methods:

  • Literature review of lectin research.
  • Analysis of studies on glycoconjugate interactions.
  • Exploration of cell recognition mechanisms involving lectins.

Main Results:

  • Plant lectins are widely used reagents for studying glycoconjugates and cell properties.
  • Lectins are key molecules in cell recognition for microorganisms and animal cells.
  • Significant potential for medical applications exists.

Conclusions:

  • Lectins are fundamental in understanding biological recognition processes.
  • Further research into lectin functions promises advancements in medicine.
  • The field of lectin research offers exciting future prospects.