Related Experiment Video
Updated: Jun 27, 2026
04:08
Mouse Model of Surgical Uterine Injury and Subsequent Pregnancy Outcomes
Published on: June 27, 2025
A pregnancy complicated by endometrial scarring
Peter C Klatsky1, Nam D Tran, Lori Strachowski
1San Francisco General Hospital, San Francisco, California, USA. pklatsky@gmail.com
Fertility and Sterility
|November 22, 2008
Summary
A woman with uterine synechiae successfully delivered a healthy baby after placental tissue implanted on both sides of her uterus. This case highlights successful pregnancy management despite uterine adhesions.
Area of Science:
- Reproductive medicine
- Obstetrics
- Maternal-fetal medicine
Background:
- Uterine synechiae, also known as Asherman syndrome, are adhesions within the uterine cavity that can impair fertility and complicate pregnancy.
- Pregnancy with placental implantation on both sides of a uterus affected by synechiae presents unique challenges.
Observation:
- A 39-year-old woman with a history of thick uterine synechiae presented with a pregnancy complicated by bilateral placental implantation.
- Serial ultrasounds were performed throughout gestation to monitor fetal development and placental positioning.
Findings:
- The patient experienced mild bleeding during the second trimester, requiring careful monitoring.
- Despite the complex uterine environment and bleeding episodes, the pregnancy progressed to term.
Implications:
- This case demonstrates the possibility of a successful term delivery in patients with significant uterine synechiae and bilateral placental implantation.
- Effective management with serial monitoring can lead to favorable outcomes in high-risk pregnancies.
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