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Updated: Jun 27, 2026

Genotypic Inference of HIV-1 Tropism Using Population-based Sequencing of V3
Published on: December 27, 2010
The five-year impact of an evolving global epidemic, changing migration patterns, and policy changes in a regional
Hartmut Krentz1, Michael John Gill
1Southern Alberta Clinic, Calgary, Alberta, Canada.
Objectives:
To evaluate the impact of policy changes to Canada's Immigration Act and changing migration patterns on a regional HIV population.
Methods:
All HIV-positive individuals enrolled in care at the Southern Alberta Cohort between 2001 and 2007 were included and subdivided by self-reported country of birth. Demographic, clinical, and health utilization data were collected at each visit. We compare data and outcomes for each group and analyze changes since policy implementation.
Results:
The proportion of immigrants/refugees increased significantly over the past five years. They present with lower CD4 counts, different HIV-subtypes, and previously rare co-morbidities. Management of disease progression necessitates more clinical visits and laboratory testing. Immigrants/refugees require greater social support to engage in, and to continue to access health care. Outcomes in HIV care were, however, equivalent to the Canadian-born population.
Conclusions:
The impact of changes to immigration policies is evident five years after implementation. Immigrant medical screening identifies increasing numbers of immigrants diagnosed with HIV. Immigrants require engagement in health care to achieve the full benefits of HIV management. Developed countries with increasing immigrant populations should be aware of how policy changes affect HIV prevalence rates, modes diagnosis and presentation, future clinical demands, and health care utilization.
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