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Published on: September 15, 2023
Evidence of improved regional myocardial function in patients with chronic stable angina and apparent normal
Gerhard-Paul Diller1, Balvinder S Wasan, Simon A McG Thom
1International Centre for Circulatory Health, St. Mary's Hospital & National Heart and Lung Institute, Imperial College, London, United Kingdom. g.diller@imperial.ac.uk
Background:
The aim of this study was to determine the impact of percutaneous coronary intervention (PCI) on myocardial function assessed by tissue Doppler echocardiography.
Methods:
Myocardial tissue peak velocities were recorded at the lateral, septal, posterior, and inferior angles of the mitral annulus as well as at the lateral tricuspid annulus by pulsed-wave tissue Doppler echocardiography before PCI, as well as 1 day and 6 weeks after intervention.
Results:
Twenty-four consecutive patients with chronic stable angina and preserved systolic left ventricular function (20 men; mean age, 64 +/- 9 years) undergoing PCI were studied. Compared with preinterventional values, early diastolic velocities improved at all sites (P < .05 for each). The most pronounced improvement occurred in the septal area. Similarly, systolic peak velocity improved in the septal, lateral, inferior, and right ventricular areas (P < .04 for each).
Conclusions:
Tissue Doppler parameters of diastolic and systolic function improve early after successful PCI, and this effect persists to 6 weeks after intervention.
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