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Updated: Jun 27, 2026

A New Method for Inducing a Depression-Like Behavior in Rats
Published on: February 22, 2018
Disability from depression: the public health challenge to primary care
1Department of Medical Humanities and Social Sciences, Florida State University College of Medicine, 1115 W. Call Street, Tallahassee, FL 32306, USA. Kathryn.Rost@med.fsu.edu
Abstract:
Epidemiologists have identified that depression will soon be the leading cause of disability throughout the world. To inform public health campaigns to reduce this problem, this paper summarizes current scientific knowledge about optimizing the potential of primary care settings to reduce disability by providing effective treatment for depression. To meet this challenge, primary care practices need to be re-engineered: 1) to conduct systematic screening programs to identify depressed patients, 2) to provide depressed patients initial evidence-based treatment, and 3) to monitor treatment adherence and symptom response in treated patients over 2 years. While additional research is needed in developing countries, preliminary evidence indicates that primary care practices re-engineered to improve depression management can make a substantial contribution to reducing depression-associated disability.
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