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Signal Attenuation as a Rat Model of Obsessive Compulsive Disorder
Published on: January 9, 2015
[Obsessive-compulsive disorder]
D S van Grootheest1, O A van den Heuvel, D C Cath
1Vrije Universiteit, afd. Biologische Psychologie, Van der Boechorststraat 1, 1081 BT Amsterdam. ds.van.grootheest@psy.vu.nl
Abstract:
Obsessive-compulsive disorder is a complex psychiatric disorder characterised by obsessions and/or compulsions. Obsessive-compulsive disorder has a relatively high prevalence and is a highly disabling disease. The disorder is associated with shame, which causes long delays in accessing treatment. Obsessive-compulsive disorder is caused by a complex interplay between genetic and environmental factors. Effective treatments exist in the form of either pharmacotherapy--clomipramine or selective serotonin reuptake inhibitors--or cognitive behaviour therapy.
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