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Clinical laboratory values during diabetic pregnancies.
F H Pilsczek1, W Renn, H Hardin
1Immunology Research Group, University of Calgary, Calgary T2N 4N1, Alberta, Canada. f.h.pilsczek@gmail.com
Journal of Ayub Medical College, Abbottabad : JAMC
|November 26, 2008
Summary
Diabetic pregnancies show similar laboratory test changes as normal pregnancies. Routine blood tests for pregnant individuals with type 1 diabetes do not require additional monitoring beyond standard pregnancy protocols.
Area of Science:
- Obstetrics and Gynecology
- Endocrinology
- Clinical Chemistry
Background:
- Physiological pregnancy alters routine laboratory tests, such as increasing erythrocyte sedimentation rate.
- Limited data exists on combined diabetes and pregnancy effects on blood test monitoring.
Purpose of the Study:
- Investigate clinical chemistry and hematological laboratory test changes in type 1 diabetic pregnancies.
- Compare these changes to those observed in normal pregnancies.
Main Methods:
- Studied 25 women with type 1 diabetes undergoing standard clinical chemistry and hematological blood tests during pregnancy.
Main Results:
- Hemoglobin, hematocrit, and erythrocyte count decreased; leucocytes and platelets showed no significant change.
- Erythrocyte sedimentation rate increased over 200%. Protein and albumin decreased below reference ranges.
- Cholesterol and triglycerides increased above normal pregnancy levels; liver enzymes remained within range.
Conclusions:
- Biochemistry and hematology values change in diabetic pregnancy, similar to physiological pregnancies.
- No additional routine laboratory testing is necessary for diabetic pregnancies compared to physiological pregnancies.
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