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Updated: Jun 27, 2026

Investigating the Effects of Antipsychotics and Schizotypy on the N400 Using Event-Related Potentials and Semantic Categorization
Published on: November 19, 2014
[The effect of excessive internet use on N400 event-related potentials]
Hongqiang Yu1, Xin Zhao, Yan Wang
1College of Precision Instrument and Optoelectronics Engineering, Tianjin University, Tianjin 300072, China. yuhongq@yahoo.com.cn
Abstract:
This investigation was made on the characteristic of the N400 event-related potentials in excessive internet users by analyzing the N400 difference between the excessive internet users (trial team) and normal subjects (control team); the aim was to provide a theoretic basis for the diagnosis and treatment of excessive internet users. Ten right-handed excessive internet users and ten healthy right-handed volunteers aged 20 to 25 years were recruited to attend the experimentation of single Chinese character with semantically matching or mismatching ending strokes. The N400 displayed obvious difference between the excessive internet users and normal subjects when they were confronted with mis-matching ending strokes of single simple Chinese character. The N400 amplitude of the trial team was significantly lower than that of the control team (P<0.05), and the N400 latency of the trial team was significantly earlier than that of the control team (P<0.05). In addition, the distribution of the N400 in the brain was more wide-spread in the control team than in the trial team. These results showed there was significant difference in N400 between the excessive internet users and the normal subjects.
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