[Bone adaptive digital analysis for femur bone being in disuse and overload condition]

Mature femur bone, through the process of bone remodeling, renews itself and adapts to mechanical load. In this study, a biomechanical model involving strain and other variable parameters was developed for bone remodeling and used to simulate the removal of bone mass and bone regeneration in the disuse and overload condition. The results exhibit that elastic modulus in bone lateral portion is decreasing and porosity is increasing for acquiring equilibrium strain. The conclusion of simulation for reality femur model is more accurate than what is obtained from simplified model or from only one volume element. These indicate the significance of acquiring scientific data to the development of consummate simulation model.