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Derivation of neurospheres from bone marrow stromal cells

A M H Ng1, K Westerman, K Kojima

  • 1Tissue Engineering Laboratories, Universiti Kebangsaan Malaysia Kuala Lumpur.

The Medical Journal of Malaysia
|November 26, 2008
PubMed

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Hemangioblasts are multipotent stem cells originating from the mesoderm. They give rise to hematopoietic stem cells (HSCs), which undergo hematopoiesis to produce all the formed elements of blood. This process is regulated by a complex network of hematopoietic growth factors, including transcription factors, growth factors, and cytokines. These factors stimulate the HSCs to divide and differentiate, though some HSCs remain undifferentiated to maintain a self-renewing pool.
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