Search research articles

Related Concept Videos

Overview of Regeneration and Repair

Overview of Regeneration and Repair

Regeneration and repair processes are critical in healing damages caused by injury, disease, and aging. In regeneration, the damaged tissue is entirely replaced with new growth that restores the original architecture and function. In contrast, tissue repair usually results in a fixed tissue architecture involving scar formation. Scars generally do not reestablish tissue function and may also exhibit structural abnormalities at the injury site.
Regeneration
All animals have varying degrees of...

Stem Cell Therapy for Tissue Regeneration

Stem Cell Therapy for Tissue Regeneration

Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
Types of Stem Cells used in Stem Cell Therapy
The two main cell types that...

Tissue Renewal without Stem Cells

Tissue Renewal without Stem Cells

After cellular or tissue damage, the resident stem cells present in the human body can locally repair and regenerate the damaged tissue or organ. However, even though some tissues do not have stem cells, they can repair and regenerate with the help of pre-existing cells. For example, beta cells of the pancreas and hepatocytes of the liver can divide to renew and regenerate the tissue. Here, both cell division and cell death are well regulated by homeostasis.
However, failure of such a system...

Tissue Transplantation

Tissue Transplantation

Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...

Healing I: Introduction

Healing I: Introduction

Healing is the physiological process by which the body restores the integrity and function of damaged tissues following injury. It involves a coordinated interplay of cellular proliferation, extracellular matrix remodeling, and growth factor signaling. The extent and nature of the tissue damage determine whether healing occurs by resolution, regeneration, or replacement.ResolutionResolution represents the most complete form of healing, occurring when the injury is minimal and tissue...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Characteristics and clinical applications of Wharton's jelly-derived mesenchymal stromal cells.

Current research in translational medicine·2019

Same author

Effect of cell density on formation of three-dimensional cartilaginous constructs using fibrin & human osteoarthritic chondrocytes.

The Indian journal of medical research·2019

Same author

Development of an In Vitro Cardiac Ischemic Model Using Primary Human Cardiomyocytes.

Cardiovascular engineering and technology·2018

Same author

Shelf Life Evaluation of Clinical Grade Chondrogenic Induced Aged Adult Stem Cells for Cartilage Regeneration.

Scientific reports·2018

Same author

Long-term evaluation of osteoarthritis sheep knee, treated with TGF-β3 and BMP-6 induced multipotent stem cells.

Experimental gerontology·2018

Same author

The evaluation of cartilage differentiations using transforming growth factor beta3 alone and with combination of bone morphogenetic protein-6 on adult stem cells.

Cell and tissue banking·2017

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Video

Updated: Jun 27, 2026

Experimental Approaches to Tissue Engineering

Experimental Approaches to Tissue Engineering

Published on: August 30, 2007

Tissue engineering provides the potential to replace and regenerate.

B H I Ruszymah¹

¹Department of Physiology, Universiti Kebangsaan Malaysia Medical Centre, Jalan Raja Muda Abdul Aziz, 50300 Kuala Lumpur.

The Medical Journal of Malaysia

|November 26, 2008

Summary

This summary is machine-generated.

Tissue engineering uses engineering and life sciences to create biological substitutes for healing. Research at Universiti Kebangsaan Malaysia Medical Centre focuses on the clinical uses of these engineered tissues.

More Related Videos

Minced Tissue in Compressed Collagen: A Cell-containing Biotransplant for Single-staged Reconstructive Repair

Minced Tissue in Compressed Collagen: A Cell-containing Biotransplant for Single-staged Reconstructive Repair

Published on: February 24, 2016

Tissue Engineering: Construction of a Multicellular 3D Scaffold for the Delivery of Layered Cell Sheets

Tissue Engineering: Construction of a Multicellular 3D Scaffold for the Delivery of Layered Cell Sheets

Published on: October 3, 2014

Related Experiment Videos

Last Updated: Jun 27, 2026

Experimental Approaches to Tissue Engineering

Experimental Approaches to Tissue Engineering

Published on: August 30, 2007

Minced Tissue in Compressed Collagen: A Cell-containing Biotransplant for Single-staged Reconstructive Repair

Minced Tissue in Compressed Collagen: A Cell-containing Biotransplant for Single-staged Reconstructive Repair

Published on: February 24, 2016

Tissue Engineering: Construction of a Multicellular 3D Scaffold for the Delivery of Layered Cell Sheets

Tissue Engineering: Construction of a Multicellular 3D Scaffold for the Delivery of Layered Cell Sheets

Published on: October 3, 2014

Area of Science:

Biomedical Engineering
Regenerative Medicine

Background:

Tissue engineering aims to restore or improve tissue and organ function.
It involves in vitro cultivation of tissues/organs for implantation when natural healing is insufficient.

Purpose of the Study:

To highlight potential clinical applications of engineered tissues.
Focuses on research conducted at the Tissue Engineering Centre, Universiti Kebangsaan Malaysia Medical Centre.

Main Methods:

Principles of engineering and life sciences are applied.
In vitro tissue and organ growth techniques are employed.

Main Results:

Research is exploring the development of biological substitutes.
The study focuses on the potential clinical translation of these advancements.

Conclusions:

Engineered tissues hold promise for therapeutic applications.
The Tissue Engineering Centre is actively researching these innovations.