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Related Concept Videos

Tissue Renewal without Stem Cells01:23

Tissue Renewal without Stem Cells

After cellular or tissue damage, the resident stem cells present in the human body can locally repair and regenerate the damaged tissue or organ. However, even though some tissues do not have stem cells, they can repair and regenerate with the help of pre-existing cells. For example, beta cells of the pancreas and hepatocytes of the liver can divide to renew and regenerate the tissue. Here, both cell division and cell death are well regulated by homeostasis.
However, failure of such a system...
Renewal of Skin Epidermal Stem Cells01:12

Renewal of Skin Epidermal Stem Cells

The skin is divided into epidermis, dermis, and hypodermis, the skin's outermost, middle, and inner layers. The human epidermal layer regularly undergoes renewal, where old, dead cells are replaced by new cells. Epidermal stem cells or EpiSCs divide and differentiate to restore the lost cells. For the renewal process, some EpiSCs continuously self-renew. In contrast, few others differentiate into transit-amplifying cells, which later form prickle or spinous cells, followed by granular cells,...
Tumor Immunotherapy01:27

Tumor Immunotherapy

Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
iPS Cell Differentiation01:22

iPS Cell Differentiation

The ability of induced pluripotent stem cells or iPSCs to differentiate into most body cell types has stimulated repair and regenerative medicine research over the past few decades. iPSC-derived blood cells, hepatocytes, beta islet cells, cardiomyocytes, neurons, and other cell types can repair injuries or regenerate damaged tissue in diseases such as diabetes and neurodegenerative disorders.
Clinical Applications of Epidermal Stem Cells01:19

Clinical Applications of Epidermal Stem Cells

Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own EpiSCs...
Stem Cell Therapy for Tissue Regeneration01:21

Stem Cell Therapy for Tissue Regeneration

Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
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The two main cell types that...

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Enhancement of Facial Rejuvenation Through a Combination of 1565 nm Non-Ablative Fractional Laser with 30% Supramolecular Salicylic Acid
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Enhancement of Facial Rejuvenation Through a Combination of 1565 nm Non-Ablative Fractional Laser with 30% Supramolecular Salicylic Acid

Published on: September 27, 2024

Cell therapy for facial anti-aging.

K Ebisawa1, R Kato, M Okada

  • 1Department of Oral and Maxillofacial Surgery, Graduate School of Medicine, Nagoya University, Nagoya, Japan.

The Medical Journal of Malaysia
|November 26, 2008
PubMed
Summary

Cultured gingival fibroblast injections offer a lasting facial anti-aging cell therapy option. Platelet-rich plasma injections show promise but require further clinical investigation.

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Enhancement of Facial Rejuvenation Through a Combination of 1565 nm Non-Ablative Fractional Laser with 30% Supramolecular Salicylic Acid
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Regenerative Therapy by Suprachoroidal Cell Autograft in Dry Age-related Macular Degeneration: Preliminary In Vivo Report

Published on: February 12, 2018

Area of Science:

  • Regenerative Medicine
  • Dermatology
  • Aesthetic Medicine

Background:

  • Facial aging presents aesthetic concerns for many individuals.
  • Cellular therapies are emerging as potential rejuvenation treatments.
  • Clinical experience guides the evaluation of novel anti-aging strategies.

Purpose of the Study:

  • To present two distinct cell therapy approaches for facial anti-aging based on clinical experience.
  • To evaluate the longevity and efficacy of cultured gingival fibroblasts for facial rejuvenation.
  • To discuss the preliminary findings and future research needs for platelet-rich plasma in facial aesthetics.

Main Methods:

  • Clinical observation and application of cultured gingival fibroblast injections.
  • Administration of platelet-rich plasma injections for facial rejuvenation.
  • Review of preliminary clinical data and patient outcomes.

Main Results:

  • Cultured gingival fibroblast injections provide sustained facial anti-aging effects for at least one year.
  • Platelet-rich plasma injections demonstrate promising preliminary results for facial rejuvenation.
  • The mechanisms and long-term efficacy of platelet-rich plasma require further elucidation.

Conclusions:

  • Cultured gingival fibroblasts represent a viable, long-lasting cell therapy for facial anti-aging.
  • Platelet-rich plasma shows potential but necessitates additional clinical data and extended follow-up.
  • Further research is crucial to fully understand and optimize platelet-rich plasma for aesthetic applications.