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Updated: Jun 27, 2026

Rapid Detection of Fecal Antigen of Helicobacter pylori Infection Based on Double Antibody Sandwich Detection Technology
Published on: May 23, 2025
[Seropositivity to Helicobacter pylori among university students and their families. A comparative cross-sectional
G Guzmán-Domínguez1, O A Newton-Sánchez, R Bustos-Saldaña
1Departamento de Salud y Bienestar, Centro Universitario del Sur, Universidad de Guadalajar, Ciudad Guzmán, Jalisco, México. gilberto.guzman@cusur.udg.mx
Objective:
To associate serologic response to Helicobacter pylori (Hp) among seropositive university students and their families in western Mexico.
Methods:
We conducted a comparative transversal study, and randomized 30 nuclear families of 14 Hp-seropositive university students and 14 Hp-seronegative university students. We carried out seropositivity measurements (IgG) to Hp using the ELISA method. An analysis was performed utilizing the chi-squared and Mann-Whitney U tests, with the aid of EPI INFO 2000 and SIGMA STAT 3.2 software.
Results:
Global seropositivity in the families of infected students was 57 vs. 13% of the relatives of non-infected students (p = 0.000002). In families of Hp-positive students we found the following frequencies: parental (father and mother) 70%; mother 71%, and siblings 42%, while for seronegative individuals incidences were: parental 17% (p = 0.00005), mother 12% (p = 0.001), and siblings 10% (p = 0.0076).
Conclusions:
There is a greater prevalence of antibodies against Hp in the relatives of seropositive students.
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