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LED phototherapy to prevent mucositis: a case report
Leticia Lang-Bicudo1, Fernanda De Paula Eduardo, Carlos De Paula Eduardo
1Mestre Profissional em Lasers em Odontologia IPEN/USP, Universidade de São Paulo, São Paulo, Brazil. leticialang@hotmail.com
Photomedicine and Laser Surgery
|November 26, 2008
Summary
Light-emitting diode (LED) phototherapy effectively prevented oral mucositis in a Hodgkin
Area of Science:
- Oncology
- Biophotonics
- Cancer Therapeutics
Background:
- Oral mucositis is a frequent, dose-limiting side effect of chemotherapy.
- Severe mucositis can compromise cancer treatment efficacy and patient survival.
- Low-level light therapies, including lasers and LEDs, show promise for mucositis management.
Observation:
- A 34-year-old male patient with Hodgkin's disease received ABVD chemotherapy.
- The patient underwent intraoral infrared LED phototherapy (880 nm) for 5 days per cycle.
- Mucositis severity and pain were assessed using WHO and VAS scales post-chemotherapy.
Findings:
- The patient experienced no oral mucositis throughout five chemotherapy cycles.
- No pain symptoms related to mucositis were reported by the patient.
- LED phototherapy demonstrated safety and efficacy in this case.
Implications:
- LED phototherapy may be a viable strategy for preventing chemotherapy-induced oral mucositis.
- Further randomized controlled trials are warranted to validate these findings.
- This approach could potentially improve treatment adherence and patient quality of life.
