Related Experiment Video
Updated: Jun 27, 2026
Technique of Conjunctival Biopsy and Direct Immunofluorescence for Diagnosing Mucous Membrane Pemphigoid
Published on: June 17, 2025
Mucous membrane pemphigoid in HIV patient: a case report
Adriana Demathé1, Lívia T Arede, Glauco I Miyahara
1Department of Pathology and Propaedeutics, School of Dentistry, Araçatuba Campus, São Paulo State University, Araçatuba, São Paulo, Brazil. adrianademathe@yahoo.com.br.
Background:
Mucous Membrane Pemphigoid (MMP) is a rare group of chronic autoimmune disorders characterized by blister producing lesions. It is the variant most likely to occur in the oral cavity and eyes. Few studies shows autoimmune bullous diseases associated with human immunodeficiency virus (HIV).
Case Presentation:
oral blisters, painful ulcerations and eye symblepharon were observed in a patient with HIV infection. The histopathologic exam showed a subepidermal blister and the overall features were suggestive of MMP.
Conclusion:
In this case, the MMP was associated with HIV. Interactions with the immune system may lead to the development of this autoimmune process.
