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Drug Repurposing Hypothesis Generation Using the "RE:fine Drugs" System
05:10

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Published on: December 11, 2016

Repeat prescribing: which diagnoses, which drugs?

J P Connolly1, H McGavock

  • 1Drug Utilization research Unit, Whitla Medical Building, Queen's University, 97 Lisburn Road, Belfast BT9 7BL.

Pharmacoepidemiology and Drug Safety
|November 26, 2008
PubMed
Summary
This summary is machine-generated.

Repeat prescribing practices vary widely among doctors, with inconsistent approaches to managing common conditions. High repeat prescription rates for certain drugs indicate potential issues needing further research.

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Area of Science:

  • General Practice
  • Health Services Research

Background:

  • Repeat prescribing guidelines recommend limiting use to stable, long-term conditions.
  • Previous studies on repeat prescribing had small sample sizes and inconsistent definitions.
  • Interpractice variation in repeat prescribing practices has not been well-described.

Purpose of the Study:

  • To identify diagnostic and drug categories associated with repeat prescriptions.
  • To quantify interpractice variation in repeat prescribing.
  • To determine repeat prescription to consultation ratios for frequent diagnoses and drugs.

Main Methods:

  • A 2-week prospective study involving 22 general practices in Northern Ireland.
  • Practitioners recorded diagnoses for all consultations and repeat prescriptions.
  • Data analysis focused on diagnostic categories, drug classes, and repeat prescription rates.

Main Results:

  • Digestive, cardiovascular, neurological, psychiatric, and metabolic diagnoses were significantly associated with repeat prescriptions (p < 0.0001).
  • Gastrointestinal, cardiovascular, central nervous system drugs, dressings, and appliances were significantly associated with repeat prescriptions (p < 0.0001).
  • Significant interpractice variation was observed in overall repeat prescribing and for specific diagnostic and drug groups. High repeat to consultation ratios were noted for ranitidine, temazepam, and diazepam.

Conclusions:

  • Wide interpractice variation in repeat prescribing suggests a lack of consensus on managing common conditions.
  • The non-uniform approach to repeat prescribing versus consultation requires further investigation.
  • Unacceptably high repeat to consultation ratios for common diagnoses and drugs warrant attention.