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Updated: Jun 27, 2026
Tracking the Mammary Architectural Features and Detecting Breast Cancer with Magnetic Resonance Diffusion Tensor Imaging
Published on: December 15, 2014
Two different types of ring-like enhancement on dynamic MR imaging in breast cancer: correlation with the
Miki Kobayashi1, Hiroko Kawashima, Osamu Matsui
1Department of Radiology, Graduate School of Medical Sciences Kanazawa University, Kanazawa, Japan. mirai@rad.m.kanazawa-u.ac.jp
Purpose:
To describe two different types of "ring-like enhancement" seen on dynamic magnetic resonance imaging (MRI) of breast cancer, and compare their histopathological features.
Materials And Methods:
A total of 326 breast carcinomas in 311 patients were evaluated regarding the existence and appearance of "ring-like enhancement" in comparison to other MR imaging and histopathological findings.
Results:
Early peripheral enhancement (EPE) was observed in 81 of 326 lesions (24.8%) and delayed rim enhancement (DRE) in 110 (33.7%). Spiculated mass, invasive ductal carcinoma with abundant stroma, central fibrosis/necrosis, and a higher degree of fat invasion correlated with EPE (P < 0.001). DRE correlated with lobulated or round mass with a smooth border, invasive ductal carcinoma with scanty stroma, higher degrees of inflammatory change and surrounding compressed tissue, and less fat invasion (P <0.001). EPE correlated with the ratio of the peripheral to central blood vessel density (P = 0.0036) and DRE with the ratio of the peritumoral to peripheral lymph vessel density (P = 0.0298).
Conclusion:
The appearance of two different types of ring-like enhancement on dynamic MRI in breast cancers was affected by the morphologic features, various histological factors reflecting the growth pattern of the mass, and angiogenesis and lymphangiogenesis.
