Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Bone Disorders01:29

Bone Disorders

Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Actuarial Approach01:20

Actuarial Approach

The actuarial approach, a statistical method originally developed for life insurance risk assessment, is widely used to calculate survival rates in clinical and population studies. This method accounts for participants lost to follow-up or those who die from causes unrelated to the study, ensuring a more accurate representation of survival probabilities.
Consider the example of a high-risk surgical procedure with significant early-stage mortality. A two-year clinical study is conducted,...
Rheumatic Heart Disease I: Introduction01:23

Rheumatic Heart Disease I: Introduction

Rheumatic heart disease or RHD is a chronic condition that results from rheumatic fever, causing permanent damage to the heart valves.Etiology and Risk FactorsIt primarily arises from rheumatic fever, an inflammatory disease that can develop after untreated or inadequately treated group A streptococcal (GAS) pharyngitis. Streptococcus spreads through direct contact with oral or respiratory secretions. While the bacteria are the causative agents, factors like malnutrition, overcrowding, poor...
Aneurysm II: Clinical Manifestations and Diagnostic Studies01:21

Aneurysm II: Clinical Manifestations and Diagnostic Studies

Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
Changes in the Appendicular Skeleton with Age01:09

Changes in the Appendicular Skeleton with Age

The upper and lower limb initially develops as a small bulge called a limb bud, which appears on the lateral side of the early embryo. The upper limb bud appears near the end of the fourth week of development, with the lower limb bud appearing shortly after.
Initially, the limb buds consist of a core of mesenchyme covered by a layer of ectoderm. The ectoderm at the end of the limb bud thickens to form a narrow crest called the apical ectodermal ridge. This ridge stimulates the underlying...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

New treatment options in ankylosing spondylitis: a role for anti-TNFalpha therapy.

Annals of the rheumatic diseases·2002
Same author

[Current status of therapeutic approaches in spondyloarthropathies].

Zeitschrift fur Rheumatologie·2002
Same author

Effective treatment of early rheumatoid arthritis with a combination of methotrexate, prednisolone and cyclosporin.

Rheumatology (Oxford, England)·2002
Same author

Brain areas specific for attentional load in a motion-tracking task.

Journal of cognitive neuroscience·2002
Same author

Infliximab treatment of severe ankylosing spondylitis: one-year followup.

Arthritis and rheumatism·2002
Same author

Magnetic resonance elastography: a method for the noninvasive and spatially resolved observation of phase transitions in gels.

Journal of the American Chemical Society·2001

Related Experiment Video

Updated: Jun 27, 2026

Du-Moxibustion in a Mouse Model of Ankylosing Spondylitis
04:47

Du-Moxibustion in a Mouse Model of Ankylosing Spondylitis

Published on: October 27, 2023

Mortality in ankylosing spondylitis.

J Zochling1, J Braun

  • 1Research Institute, Hobart, Australia.

Clinical and Experimental Rheumatology
|December 17, 2008
PubMed
Summary
This summary is machine-generated.

Ankylosing spondylitis (AS) patients face higher mortality rates due to cardiovascular issues and psychological health problems. Addressing these risks alongside physical disability is crucial for improving patient outcomes.

More Related Videos

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
04:44

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

Published on: June 16, 2020

Related Experiment Videos

Last Updated: Jun 27, 2026

Du-Moxibustion in a Mouse Model of Ankylosing Spondylitis
04:47

Du-Moxibustion in a Mouse Model of Ankylosing Spondylitis

Published on: October 27, 2023

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
04:44

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

Published on: June 16, 2020

Area of Science:

  • Rheumatology
  • Public Health

Background:

  • Ankylosing spondylitis (AS) is a chronic inflammatory disease impacting physical function and quality of life.
  • AS is associated with increased mortality compared to the general population.

Purpose of the Study:

  • To review the rates and causes of increased mortality in AS patients.
  • To highlight the need for comprehensive patient care focusing on cardiovascular and psychological health.

Main Methods:

  • Literature review examining mortality rates and causes in AS.
  • Analysis of cardiovascular risk factors, lipid regulation, and microvascular changes.
  • Review of psychological health impacts, including suicide and alcohol-related deaths.

Main Results:

  • Increased cardiovascular deaths are observed in AS patients.
  • Abnormalities in lipid regulation and microvascular changes are suggested.
  • Higher rates of suicide, accidental, and alcohol-related deaths are reported.

Conclusions:

  • AS significantly increases mortality risk.
  • Cardiovascular risk factors and psychological health require focused attention in AS management.
  • Integrated care addressing physical, cardiovascular, and psychological aspects is essential for AS patients.