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Updated: Jun 27, 2026
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miRNA Expression Analyses in Prostate Cancer Clinical Tissues
Published on: September 8, 2015
Gene expression profile in the peripheral blood of patients with prostate cancer and benign prostatic hyperplasia
Cancer Detection and Prevention
|November 26, 2008
Abstract
Background:
Prostate cancer consists of multifactorial and multifocal events, generating differential gene expression in tumor cells.
Methods:
The molecular profile of 14 gene expression was analyzed through cDNA array in blood samples of patients with prostate cancer (PCa) and benign prostatic hyperplasia (BPH).
Results:
Messenger RNA from patient's blood showed significant differences between PCa and BPH groups only for the NOS3 gene, with an occurrence chance for PCa5.8-fold higher than BPH disease.
Conclusion:
The NOS3 gene expression in the patient's blood may be used as a putative biomarker for prostate cancer.
