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Novel Percutaneous Approach for Deployment of 3D Printed Coronary Stenosis Implants in Swine Models of Ischemic Heart Disease
Published on: February 18, 2020
Genesis stent implantation without using a long sheath in two children
Toshiyuki Kobayashi1, Hideshi Tomita, Masato Yokozawa
1Department of Pediatrics, Urakawa Redcross Hospital, 1-2-1 Higashimachi-chinomi, Urakawa-cho, Hokkaido 057-0007, Japan. ktoshi@sapmed.ac.jp
Journal of Cardiology
|November 26, 2008
Summary
The Genesis stent effectively treated stenosis in two pediatric cases, improving blood flow in the superior vena cava and pulmonary artery. Its design allows for easier delivery in infants and children, offering a promising solution for vascular stenosis.
Area of Science:
- Cardiology
- Pediatric Interventional Cardiology
- Biomedical Engineering
Background:
- Congenital heart defects can lead to vascular stenosis, requiring interventions in pediatric patients.
- Superior vena cava (SVC) stenosis and pulmonary artery branch stenosis are critical conditions affecting blood circulation.
- Previous interventions for these conditions may have limitations in pediatric cases.
Observation:
- A Genesis stent was implanted in two children with distinct forms of vascular stenosis.
- Case 1 involved a 2-month-old infant with SVC stenosis post-total anomalous pulmonary venous connection (TAPVC) repair.
- Case 2 involved a 2-year-old child with left lower pulmonary artery stenosis following complex congenital heart defect repair.
Findings:
- Both Genesis stent implantations resulted in immediate clinical and hemodynamic improvements.
- The stent's closed-cell design with sigma hinges facilitated its deliverability and expandability.
- Successful deployment was achieved through smaller sheaths, indicating suitability for pediatric vasculature.
Implications:
- The Genesis stent demonstrates potential as an effective treatment for pediatric vascular stenosis.
- Its improved characteristics may enhance procedural success rates and reduce complications in infants and children.
- This technology could expand treatment options for complex congenital heart disease patients requiring vascular interventions.

