Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Drug Abuse and Addiction: Pharmacological Phenomena01:15

Drug Abuse and Addiction: Pharmacological Phenomena

Drug dependence, abuse, and addiction are complex phenomena that can precipitate various abnormal states. Physical dependence refers to a state of pharmacological adaptation to a drug. This adaptation often results in tolerance—a reduced response to the drug after repeated administrations. When the drug use is abruptly stopped, withdrawal symptoms occur due to the body's need to readjust from the pharmacologically induced imbalance. However, tolerance and withdrawal symptoms do not necessarily...
Drug Dependence01:17

Drug Dependence

Medications are typically administered to achieve therapeutic effects. Some drugs can modify an individual's mood and perception, frequently resulting in various enjoyable experiences. However, this can result in drug dependency, a condition marked by continuous drug use despite potential negative consequences. Drug dependency primarily falls into two categories: psychological and physical dependence. Psychological dependence occurs when the pleasurable feelings induced by the drug...
Substance Use Disorders Affecting Sleep01:24

Substance Use Disorders Affecting Sleep

Substance use disorders involve a pattern of using drugs more extensively than intended and continuing use despite harmful consequences. This includes legal substances like alcohol and nicotine, as well as illegal drugs. These disorders often involve both physical and psychological dependence, reflecting compulsive use of substances that significantly alter thoughts, feelings, and behaviors, contributing to a major public health issue.
Understanding the concepts of physical dependence,...
Dosage Regimens: Designs and Approaches01:28

Dosage Regimens: Designs and Approaches

Designing a dosage regimen, which refers to the manner of drug administration, is a complex process involving the selection of drug dose, route, and frequency. This process is underpinned by pharmacokinetic parameters derived from tests and population averages. These parameters are then tailored to patient-specific variables such as diagnosis, demographics, and allergy status. Once therapy commences, therapeutic response monitoring is critical and achieved through clinical and physical...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Spring Broken: A Risk Analysis of Fatal and Nonfatal Traffic Injuries in Florida.

Risk analysis : an official publication of the Society for Risk Analysis·2026
Same author

Is a Distressed Birth Associated With Physical and Mental Health Problems as an Adult?: Evidence From Panel Data.

Medical care·2025
Same author

Do Current and Lifetime Mental Health Issues Influence Subjective Social Status?

The journal of mental health policy and economics·2025
Same author

Use of alternative payment models for substance use disorder prevention in the United States: development of a conceptual framework.

Substance abuse treatment, prevention, and policy·2025
Same author

Quality-Adjusted Life Years, Quality-Adjusted Life-Year-Like Measures, or Neither? The Debate Continues.

Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research·2024
Same author

Hit-and-run or hit-and-stay? Unintended effects of a stricter BAC limit.

Risk analysis : an official publication of the Society for Risk Analysis·2024

Related Experiment Video

Updated: Jun 27, 2026

Integrating Computerized Linguistic and Social Network Analyses to Capture Addiction Recovery Capital in an Online Community
08:53

Integrating Computerized Linguistic and Social Network Analyses to Capture Addiction Recovery Capital in an Online Community

Published on: May 31, 2019

Economic evaluation of adolescent addiction programs: methodologic challenges and recommendations.

Jenny F Homer1, Michael F Drummond, Michael T French

  • 1Health Economics Research Group, University of Miami, Coral Gables, Florida 33124-2030, USA.

The Journal of Adolescent Health : Official Publication of the Society for Adolescent Medicine
|November 26, 2008
PubMed
Summary

Economic evaluations of adolescent substance abuse interventions face methodologic challenges in study design, cost estimation, and generalizability. This article offers recommendations for overcoming these issues in addiction research.

More Related Videos

A Procedure to Study Stress-Induced Relapse of Heroin Seeking after Punishment-Imposed Abstinence
08:05

A Procedure to Study Stress-Induced Relapse of Heroin Seeking after Punishment-Imposed Abstinence

Published on: March 23, 2022

Investigating Drivers of Antireward in Addiction Behavior with Anatomically Specific Single-Cell Gene Expression Methods
09:29

Investigating Drivers of Antireward in Addiction Behavior with Anatomically Specific Single-Cell Gene Expression Methods

Published on: August 4, 2022

Related Experiment Videos

Last Updated: Jun 27, 2026

Integrating Computerized Linguistic and Social Network Analyses to Capture Addiction Recovery Capital in an Online Community
08:53

Integrating Computerized Linguistic and Social Network Analyses to Capture Addiction Recovery Capital in an Online Community

Published on: May 31, 2019

A Procedure to Study Stress-Induced Relapse of Heroin Seeking after Punishment-Imposed Abstinence
08:05

A Procedure to Study Stress-Induced Relapse of Heroin Seeking after Punishment-Imposed Abstinence

Published on: March 23, 2022

Investigating Drivers of Antireward in Addiction Behavior with Anatomically Specific Single-Cell Gene Expression Methods
09:29

Investigating Drivers of Antireward in Addiction Behavior with Anatomically Specific Single-Cell Gene Expression Methods

Published on: August 4, 2022

Area of Science:

  • Health Economics
  • Adolescent Health
  • Substance Abuse Research

Background:

  • Economic evaluations are crucial for assessing the value of substance abuse interventions for adolescents.
  • Methodologic rigor is essential for reliable and valid economic assessments in this field.
  • Adolescent substance abuse presents unique challenges for economic evaluation.

Purpose of the Study:

  • To identify and describe key methodologic challenges in economic evaluations of adolescent substance abuse interventions.
  • To provide recommendations for addressing these challenges.
  • To enhance the quality and applicability of economic research in adolescent addiction.

Main Methods:

  • Literature review and synthesis of methodologic issues in economic evaluations.
  • Analysis of challenges related to study design, perspective, cost estimation, and outcome measurement.
  • Case examples from adolescent substance abuse and dependency/addiction research.

Main Results:

  • Identified challenges include appropriate study design, selecting the correct economic perspective (e.g., societal, healthcare), accurately estimating intervention and healthcare costs, and measuring relevant outcomes.
  • Generalizability of findings across diverse adolescent populations and settings is a significant concern.
  • Specific examples illustrate the complexities in evaluating interventions for adolescent substance use disorders.

Conclusions:

  • Addressing these methodologic challenges is vital for robust economic evaluations of adolescent substance abuse interventions.
  • Recommendations focus on improving study design, cost-effectiveness analysis, and outcome assessment.
  • Enhanced economic evaluations can better inform policy and practice for adolescent addiction treatment and prevention.