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Related Experiment Video

Updated: Jun 27, 2026

Transperineal Prostate Biopsy Using a Cone-shaped Double-hole Method with Dual-plane Probe Guidance
05:35

Transperineal Prostate Biopsy Using a Cone-shaped Double-hole Method with Dual-plane Probe Guidance

Published on: June 6, 2025

Stereotactic transperineal prostate biopsy.

Brian J Moran1, Michelle H Braccioforte

  • 1Prostate Cancer Foundation of Chicago, Westmont, Illinois 60559, USA. seeds@protateimplant.com

Urology
|November 26, 2008
PubMed
Summary

Stereotactic transperineal prostate biopsy (STPB) improves detection of occult prostate cancer missed by prior biopsies. This technique is effective for finding nonpalpable, isoechoic prostate malignancies.

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Area of Science:

  • Urology
  • Oncology
  • Medical Imaging

Background:

  • Prostate cancer is a leading cause of cancer death in men.
  • Detecting occult prostate malignancy can be challenging, especially for nonpalpable, isoechoic lesions.
  • Previous transrectal ultrasound-guided biopsies may fail to detect all malignancies.

Purpose of the Study:

  • To evaluate the detection rate of nonpalpable, isoechoic prostate cancer.
  • To assess the efficacy of stereotactic transperineal prostate biopsy (STPB) in patients with prior negative biopsies.

Main Methods:

  • Utilized a stereotactic transperineal prostate biopsy (STPB) technique.
  • Included patients with previously negative transrectal ultrasound-guided prostate biopsies.
  • Focused on detecting nonpalpable, isoechoic prostate tumors.

Main Results:

  • STPB demonstrated a significant detection rate for occult prostate malignancies.
  • The technique successfully identified isoechoic lesions previously missed.
  • This method offers improved diagnostic yield in challenging cases.

Conclusions:

  • Stereotactic transperineal prostate biopsy is a valuable tool for detecting occult prostate cancer.
  • STPB enhances the detection of nonpalpable, isoechoic prostate malignancies.
  • This biopsy approach improves diagnostic accuracy in patients with prior negative results.

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Last Updated: Jun 27, 2026

Transperineal Prostate Biopsy Using a Cone-shaped Double-hole Method with Dual-plane Probe Guidance
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Transperineal Prostate Biopsy Using a Cone-shaped Double-hole Method with Dual-plane Probe Guidance

Published on: June 6, 2025

Use of MRI-ultrasound Fusion to Achieve Targeted Prostate Biopsy
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Use of MRI-ultrasound Fusion to Achieve Targeted Prostate Biopsy

Published on: April 9, 2019