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Related Concept Videos

Genetic Screens02:46

Genetic Screens

Genetic screens are tools used to identify genes and mutations responsible for phenotypes of interest. Genetic screens help identify individuals or a group of people at risk of developing  genetic diseases and help them with early intervention, targeted therapy, and reproductive options.
Forward genetic screens
Forward or “classical” genetic screens involve creating random mutations in an organism’s DNA using radiation, mutagens, or insertion of additional bases, which result in visible changes...
Genomics02:02

Genomics

Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...

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Related Experiment Video

Updated: Jun 27, 2026

Tick Microbiome Characterization by Next-Generation 16S rRNA Amplicon Sequencing
07:21

Tick Microbiome Characterization by Next-Generation 16S rRNA Amplicon Sequencing

Published on: August 25, 2018

VectorBase: a data resource for invertebrate vector genomics.

Daniel Lawson1, Peter Arensburger, Peter Atkinson

  • 1European Bioinformatics Institute (EMBL-EBI), Wellcome Trust Genome Campus, Hinxton, Cambridgeshire CB10 1SD, UK. lawson@ebi.ac.uk

Nucleic Acids Research
|November 26, 2008
PubMed
Summary
This summary is machine-generated.

VectorBase provides curated genomic data for invertebrate disease vectors, enhancing research accessibility. This bioinformatics resource now includes community annotation and gene expression data for key species.

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Last Updated: Jun 27, 2026

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Published on: June 28, 2012

Area of Science:

  • Bioinformatics
  • Genomics
  • Invertebrate Biology

Background:

  • VectorBase is a NIAID-funded Bioinformatics Resource Center.
  • Focuses on invertebrate vectors of human pathogens.
  • Provides annotated and curated vector genomes for researchers.

Purpose of the Study:

  • To present updates on the VectorBase resource.
  • To highlight new features and expanded data.
  • To emphasize its role as an integrated research tool.

Main Methods:

  • Genome annotation and curation.
  • Development of a community annotation system.
  • Integration of microarray and gene expression data.
  • Creation of controlled vocabularies for anatomy and insecticide resistance.
  • Software infrastructure and data interrogation tool development.

Main Results:

  • VectorBase now includes genome information for Aedes aegypti, Anopheles gambiae, Culex quinquefasciatus, Pediculus humanus, and Ixodes scapularis.
  • New features include a community annotation system, a microarray and gene expression repository, and controlled vocabularies.
  • Ongoing development of software infrastructure and data interrogation tools.

Conclusions:

  • VectorBase serves as a vital, integrated resource for studying invertebrate vectors.
  • The addition of new features enhances data accessibility and research capabilities.
  • Continued development ensures VectorBase remains a cutting-edge bioinformatics platform.