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Related Concept Videos

Tooth Anatomy01:21

Tooth Anatomy

The human tooth enables us to eat a variety of foods, speak clearly, and even aid in shaping our faces. Teeth are composed of various elements that work together. Here's a detailed look at the anatomy of a human tooth.
The Crown, Neck, and Root
The visible part of the tooth is referred to as the crown. It's covered by enamel, the hardest substance in the human body. The crown is uniquely shaped for each type of tooth, allowing for different functions such as cutting, tearing, or grinding food.

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Related Experiment Video

Updated: Jun 27, 2026

Tissue Engineering by Intrinsic Vascularization in an In Vivo Tissue Engineering Chamber
09:55

Tissue Engineering by Intrinsic Vascularization in an In Vivo Tissue Engineering Chamber

Published on: May 30, 2016

Vascularization of engineered teeth.

A Nait Lechguer1, S Kuchler-Bopp, B Hu

  • 1INSERM UMR 595, Faculté de Médecine, 11, rue Humann, 67085 Strasbourg cedex, France.

Journal of Dental Research
|November 26, 2008
PubMed
Summary
This summary is machine-generated.

Vascularization is key for tooth development and regeneration. Implanted cultured teeth and cell re-associations successfully revascularize, enabling organ growth, mineralization, and enamel secretion for tissue engineering.

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Area of Science:

  • Dental research
  • Tissue engineering
  • Developmental biology

Background:

  • Tooth development involves complex morphogenesis and histogenesis.
  • Vascularization is essential for organogenesis and successful tissue engineering.
  • Understanding blood vessel behavior in cultured dental tissues is crucial for regenerative applications.

Purpose of the Study:

  • To investigate blood vessel formation during tooth development.
  • To analyze the fate of blood vessels in cultured teeth and cell re-associations.
  • To examine vascularization following in vivo implantation of dental tissues.

Main Methods:

  • Ex vivo analysis of blood vessel development in dental tissues.
  • In vitro culture of teeth and cell re-associations.
  • In vivo implantation and subsequent vascularization assessment.

Main Results:

  • Blood vessels form in dental mesenchyme and enamel organ during development.
  • Cultured dental tissues show limited vascular development within dental structures.
  • Implanted teeth and re-associations achieve host-derived revascularization, supporting tissue survival and function.

Conclusions:

  • Successful revascularization of implanted dental tissues is critical for regeneration.
  • Host blood vessel integration enables organ growth, mineralization, and enamel secretion in re-associations.
  • This study provides insights into vascularization strategies for dental tissue engineering.