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Vancomycin-resistant Enterococcus faecalis in a bone-marrow transplant recipient.

W E Peetermans¹, F W Sebens, H F Guiot

¹Department of Infectious Diseases, University Hospital Leiden, The Netherlands.

Scandinavian Journal of Infectious Diseases

|January 1, 1991

Summary

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Vancomycin-resistant Enterococcus faecalis (VRE) can colonize and infect patients, even those without prior vancomycin exposure. This case highlights VRE

Area of Science:

Infectious Diseases
Microbiology
Clinical Medicine

Background:

Vancomycin-resistant enterococci (VRE) emergence is a growing concern in healthcare settings.
Enterococcus faecalis is a common cause of VRE infections.
Understanding VRE epidemiology and resistance mechanisms is crucial for effective treatment.

Observation:

A bone-marrow transplant recipient developed colonization and subsequent infection with VRE.
The patient had no prior history of vancomycin therapy.
The VRE strain exhibited resistance to multiple antibiotics, including gentamicin and teicoplanin.

Findings:

The VRE strain was sensitive to amoxicillin and daptomycin.
This case adds to the reports on VRE emergence.

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The origin and acquisition of VRE remain largely unknown.

Implications:

This case underscores the need for vigilance in VRE surveillance, especially in immunocompromised patients.
Further research is required to elucidate VRE origins and transmission routes.
Identifying effective antibiotic treatments, such as amoxicillin and daptomycin, is vital for managing VRE infections.