Related Experiment Video
Updated: Jun 27, 2026

SECONDs Administration Guidelines: A Fast Tool to Assess Consciousness in Brain-injured Patients
Published on: February 6, 2021
When are episodes of loss of consciousness life-threatening?
Paula Brna1, Peter Camfield, Carol Camfield
1Department of Pediatrics, IWK Health Centre and Dalhousie University, Halifax, Nova Scotia.
Insights
Recurrent loss of consciousness in children can stem from serious cardiac issues like Brugada syndrome, not just epilepsy. Prompt identification of cardiac causes is critical to prevent potentially fatal outcomes.
Area of Science:
- Pediatric Cardiology
- Neurology
- Genetics
Background:
- Episodic loss of consciousness is frequent in children.
- Most causes are benign, but life-threatening conditions require immediate attention.
- Distinguishing neurological from cardiac etiologies is crucial.
Purpose of the Study:
- To present a case of Brugada syndrome presenting as recurrent loss of consciousness with seizures and cardiac arrest in a child.
- To emphasize the diagnostic challenges in differentiating epilepsy from convulsive syncope.
- To review pediatric causes of paroxysmal loss of consciousness and highlight features of cardiac etiology.
Main Methods:
- Case report presentation.
- Review of pediatric causes of paroxysmal loss of consciousness.
- Emphasis on clinical features suggestive of cardiac origin.
Main Results:
- A rare case of Brugada syndrome causing recurrent loss of consciousness, seizures, and cardiac arrest is detailed.
- The case illustrates the difficulty in differentiating epilepsy from cardiac syncope.
- Undiagnosed cardiac conditions can have severe consequences.
Conclusions:
- Brugada syndrome is a rare but critical cause of syncope in children.
- Clinical vigilance for cardiac signs is essential in evaluating pediatric loss of consciousness.
- Early diagnosis and management of cardiac causes can be life-saving.
Abstract:
Episodic loss of consciousness is common in the paediatric population. While the majority of cases are due to benign conditions, life-threatening causes must be promptly identified.The present paper presents a case of recurrent loss of consciousness associated with convulsive activity and subsequent cardiac arrest due to a rare inherited ion channel disease known as Brugada syndrome. The case highlights the challenges of distinguishing epilepsy from convulsive syncope and the potentially disastrous consequences of an undiagnosed cardiac etiology. The most important paediatric causes of paroxysmal loss of consciousness and their salient features are reviewed. Clinical features suggesting a cardiac cause are emphasized because early recognition of these cases is critical.
Related Concept Videos
Seizures l: Introduction
Seizures ll: Types
Traumatic Brain Injury l: Introduction
Pneumothorax-I
Pneumothorax can be even further classified as spontaneous, traumatic, and tension pneumothorax.
Stages of General Anesthesia
Introduction Cardiac Emergencies

