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The Neuropsychiatric Inventory--NPI. Validation of the Danish version
Alex Kørner1, Lise Lauritzen, Annette Lolk
1Psychogeriatric Clinic, Psychiatric Hospital, Hillerød, Denmark. alko@noh.regionh.dk
Nordic Journal of Psychiatry
|November 26, 2008
Summary
The Danish NPI is a valid and reliable tool for assessing neuropsychiatric symptoms in dementia patients. However, it is not fully scalable, so using individual item scores is recommended over the total score.
Area of Science:
- Neuroscience
- Gerontology
- Psychiatry
Background:
- Neuropsychiatric symptoms are common in dementia and significantly impact clinical care.
- Accurate assessment tools are crucial for managing dementia patients.
Purpose of the Study:
- To validate the Danish version of the Neuropsychiatric Inventory (NPI).
- To assess the reliability and scalability of the Danish NPI in elderly individuals with and without dementia.
Main Methods:
- The study involved 72 demented and 29 non-demented participants (age 65+) and their caregivers over three visits.
- The Danish NPI was administered by a psychiatric nurse, with concurrent assessments using ICD-10, GDS, CGI, and an NPI-Visual Analogue Scale (VAS) version.
- Inter-rater reliability (ICC), test-retest reliability, and scalability (Mokken, Loevinger coefficients) were analyzed.
Main Results:
- High inter-rater reliability (ICC > 0.80) was found for NPI domains and GDS.
- Satisfactory to perfect reliability was observed for NPI-VAS (0.68-0.95) and CGI (0.69).
- High correlations between NPI and NPI-VAS scores were noted, except for depression and agitation/aggression. NPI scores correlated with dementia severity. The NPI did not meet scalability criteria.
Conclusions:
- The Danish NPI is a valid and reliable instrument for assessing neuropsychiatric symptoms in dementia.
- The NPI is not fully scalable; therefore, the use of single item scores is recommended over the total sum score for clinical application.
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