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Published on: November 21, 2013
Deteriorated visual backward masking in the shine-through effect in adolescents with psychosis
Laurent Holzer1, Laure Jaugey, Leonie Chinet
1Centre Thérapeutique de Jour pour Adolescents, Service Universitaire de Psychiatrie de l'Enfant et de l'Adolescent, 1012 Lausanne, Switzerland. Laurent.holzer@chuv.ch
Abstract:
Visual backward masking is a reliable and widely used tool in schizophrenia research. Whereas many studies have shown masking deficits in adult patients, there are only very few studies with adolescents with psychosis-and with controversial results. Masking deficits of adolescents are of primary interest because they are not caused by long-term suffering from the disease and severe medication. We investigated 15 adolescents with psychosis and 19 age-matched controls in the shine-through backward masking paradigm for which strong performance deficits were shown previously in adult schizophrenic patients and their relatives. Adolescents with psychosis were strongly impaired in the shine-through effect compared to controls. This result adds further evidence that backward masking is an endophenotype of schizophrenia.
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