Related Experiment Video

Updated: Jun 27, 2026

Concurrent Collection of Fetal Murine Brain and Serum to Assess Effects of Maternal Diet on Nutrition and Neurodevelopment in Neurofibromatosis Type 1
05:44

Concurrent Collection of Fetal Murine Brain and Serum to Assess Effects of Maternal Diet on Nutrition and Neurodevelopment in Neurofibromatosis Type 1

Published on: May 17, 2024

[Relations between pre-pregnancy body mass index, gestational weight gain, and the occurrence of neonatal asphyxia]

Ying-hui Liu1, Jian-meng Liu, Wei-hong Liu

  • 1Institute of Reproductive and Child Health, Peking University Health Science Center, Beijing 100083, China.

Zhonghua Liu Xing Bing Xue Za Zhi = Zhonghua Liuxingbingxue Zazhi
|November 27, 2008
PubMed

Insights

Lower gestational weight gain may increase the risk of neonatal asphyxia. This study highlights the importance of monitoring weight gain during pregnancy for improved infant outcomes.

Area of Science:

  • Obstetrics and Gynecology
  • Neonatal Health
  • Public Health Research

Context:

  • Investigated the relationship between maternal pre-pregnancy body mass index (BMI) and gestational weight gain on neonatal asphyxia risk.
  • Utilized data from 83,030 women in Jiaxing, Zhejiang province, China, from 1995-2000.
  • Employed statistical analyses including Chi-square tests and multivariate logistic regression.

Purpose:

  • To assess the association between pre-pregnancy BMI, weight gain during pregnancy, and the risk of neonatal asphyxia.
  • To identify potential risk factors for neonatal asphyxia related to maternal weight management.
  • To provide evidence for optimizing prenatal care guidelines.

Summary:

  • The study found that lower gestational weight gain (<0.3 kg/wk or 0.3-0.4 kg/wk) was associated with an increased risk of neonatal asphyxia.
  • While pre-pregnancy BMI showed some trends, the association was less pronounced after adjusting for covariates.
  • The average rate of neonatal asphyxia was 11.3% in the study population.

Impact:

  • Findings suggest that inadequate weight gain during pregnancy could be a modifiable risk factor for neonatal asphyxia.
  • Highlights the need for individualized nutritional guidance and monitoring of gestational weight gain.
  • Contributes to understanding perinatal health outcomes and informing public health interventions.
Abstract

More Related Videos

A Swine Model of Neonatal Asphyxia10:36

A Swine Model of Neonatal Asphyxia

Published on: October 11, 2011

Related Concept Videos

Pathophysiology of Diabetes01:20

Pathophysiology of Diabetes

Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility, suggesting a...
Anorexia Nervosa01:28

Anorexia Nervosa

Anorexia nervosa is a complex and severe eating disorder characterized by an intense fear of weight gain, an unrelenting pursuit of thinness, and a distorted body image. It often leads to dangerously low body weight relative to an individual's age and height. This disorder is marked by significant physical and psychological consequences, making it one of the most life-threatening psychiatric illnesses.
Symptoms and Physical Effects
Individuals with anorexia nervosa commonly exhibit extreme...
Obesity01:24

Obesity

The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in adipocytes...
Diabetes Mellitus: Type 2 and Gestational01:22

Diabetes Mellitus: Type 2 and Gestational

Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
Teratogenicity01:07

Teratogenicity

The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
Bulimia Nervosa01:30

Bulimia Nervosa

Bulimia nervosa is a complex and severe eating disorder characterized by a cyclical pattern of binge-and-purge eating pattern. It generally involves an episode of binge eating, followed by compensatory behaviors such as vomiting, excessive exercise, laxative use, or fasting, to prevent weight gain. Despite often maintaining a normal weight, individuals with bulimia are intensely preoccupied with their body image and harbor an overwhelming fear of gaining weight. This can contribute to the...