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Updated: Jun 27, 2026
Two Methods for Establishing Primary Human Endometrial Stromal Cells from Hysterectomy Specimens
Published on: May 23, 2014
Low-grade endometrial stromal sarcoma of the uterus: review of 10 cases
Vincent Landréat1, Nicolas Paillocher, Laurent Catala
1Department of Obstetric Gynaecology, University Hospital, F-35203 Rennes Cedex 2, France.
Background:
Low-grade endometrial sarcoma is a rare gynecological tumor (0.2% of female genital tract tumors) mainly observed in women before their 50's.
Patients And Methods:
The authors present a series of 10 patients followed in two institutions and describe the treatment administered (cytoreductive surgery, i.e. bilateral annexectomy and total hysterectomy, and medical treatments) and the follow-up.
Results And Discussion:
Local recurrence occurred in 70% of cases, whereas metastasis was rare even after suboptimal surgical removal of the tumor. Adjuvant progestin therapy is currently the most effective treatment for curing and preventing local recurrence. The use of aromatase inhibitors is a promising research approach.
