Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Mitral Valve Prolapse III: Nursing Management

Mitral Valve Prolapse III: Nursing Management

The nursing management of Mitral Valve Prolapse, or MVP, centers around patient education, symptom monitoring, and lifestyle modifications.Patient Education on MVP Diagnosis and Heredity: Nurses should provide comprehensive education about MVP, a condition where the mitral valve does not close appropriately during heartbeats. This education often includes the condition's pathophysiology, symptoms, and potential complications, like arrhythmias or mitral regurgitation. Though not fully...

Ovarian Cycle

Ovarian Cycle

The menstrual cycle includes a critical component known as the ovarian cycle, which undergoes two main phases each month—the follicular phase and the luteal phase. The follicular phase is variable and averaging around 14 days. Ovulation, triggered by a surge in luteinizing hormone (LH), marks the transition between the two phases. The second phase, the luteal phase, is relatively consistent, lasting approximately 14 days, and is marked by the activity of the corpus luteum. While a cycle length...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Increasing Uptake of COVID-19 Vaccination and Reducing Health Inequalities in Patients on Renal Replacement Therapy-Experience from a Single Tertiary Centre.

Vaccines·2022

Same author

Predictive Analysis of Gallbladder Wall Thickness as a Marker for Bleeding Risk and Need for Transfusion in Dengue Patients.

Japanese journal of infectious diseases·2021

Same author

Assessing the Mental Impact and Burnout among Physicians during the COVID-19 Pandemic: A Developing Country Single-Center Experience.

The American journal of tropical medicine and hygiene·2021

Same author

Impact of Fasting Lipid Profile on Chronic Kidney Disease Patients Having Fatty Liver Disease.

Cureus·2020

Same author

Pericardial Tumor, a Rare Manifestation of Sjogren's Syndrome Secondary to Systemic Lupus Erythematosus.

Cureus·2020

Same author

Massive Ovarian Edema Mimicking Malignancy.

Journal of the College of Physicians and Surgeons--Pakistan : JCPSP·2020

Search research articles

Related Experiment Video

Updated: Jun 27, 2026

Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas

Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas

Published on: January 17, 2018

Pregnancy with macroprolactinoma.

Shazia Abid¹, Iftikhar Sadiq, Saira Anwar

¹Department of Obstetrics and Gynaecology, Sharif Medical and Dental Hospital, Lahore. dr_shaziaabid@hotmail.com

Journal of the College of Physicians and Surgeons--Pakistan : JCPSP

|November 27, 2008

Summary

A recurrent macroprolactinoma caused vision loss during pregnancy. Surgical removal improved vision, but medication adjustments were needed to manage elevated prolactin levels.

More Related Videos

X-Ray Visualization of Intraductal Ethanol-Based Ablative Treatment for Prevention of Breast Cancer in Rat Models

X-Ray Visualization of Intraductal Ethanol-Based Ablative Treatment for Prevention of Breast Cancer in Rat Models

Published on: December 9, 2022

Related Experiment Videos

Last Updated: Jun 27, 2026

Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas

Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas

Published on: January 17, 2018

X-Ray Visualization of Intraductal Ethanol-Based Ablative Treatment for Prevention of Breast Cancer in Rat Models

X-Ray Visualization of Intraductal Ethanol-Based Ablative Treatment for Prevention of Breast Cancer in Rat Models

Published on: December 9, 2022

Area of Science:

Endocrinology
Neuro-oncology
Reproductive Medicine

Background:

Macroprolactinomas, a type of pituitary tumor, can cause infertility, amenorrhea, and galactorrhea.
Tumor growth during pregnancy can lead to significant complications, including visual impairment due to optic chiasm compression.

Purpose of the Study:

To report a case of recurrent macroprolactinoma presenting with visual loss during pregnancy.
To discuss the management challenges and treatment outcomes in such cases.

Main Methods:

Case presentation of a 25-year-old female with recurrent macroprolactinoma.
Diagnostic workup including MRI and serum prolactin levels.
Treatment modalities included bromocriptine, transsphenoidal adenectomy, and lisuride hydrogen.

Main Results:

Initial bromocriptine treatment normalized prolactin and restored fertility.
Tumor enlargement during pregnancy caused severe headache and vision loss.
Transsphenoidal adenectomy improved visual fields, but prolactin remained elevated.
Post-surgery, bromocriptine (15 mg/day) was ineffective, but lisuride hydrogen (0.8 mg/day) successfully reduced prolactin levels.

Conclusions:

Recurrent macroprolactinoma poses significant risks during pregnancy, necessitating careful monitoring.
Multimodal treatment including surgery and pharmacotherapy is crucial for managing these complex cases.
Lisuride hydrogen demonstrated efficacy in controlling hyperprolactinemia when bromocriptine failed.