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Updated: Jun 27, 2026

Echocardiographic Evaluation of Atrial Communications before Transcatheter Closure
Published on: February 8, 2022
Echocardiographic evaluation of left atrial size and function: current understanding, pathophysiologic correlates,
Dominic Y Leung1, Anita Boyd, Arnold A Ng
1Liverpool Hospital, University of New South Wales, Sydney, New South Wales, Australia.
Insights
Left atrial (LA) volume is a potential biomarker for heart and cerebrovascular diseases. This review explores echocardiographic methods to assess LA size and function, clarifying its prognostic value.
Area of Science:
- Cardiology
- Echocardiography
- Biomarkers
Background:
- Left atrial (LA) volume is recognized as a potential biomarker for cardiovascular and cerebrovascular diseases.
- The prognostic implications of LA volume require further clarification.
- Assessing LA size and function via echocardiography is feasible in routine clinical practice.
Purpose of the Study:
- To review conventional and novel echocardiographic parameters for evaluating LA size and function.
- To discuss the clinical relevance and implications of an enlarged left atrium based on current literature.
Main Methods:
- Discussion of conventional echocardiographic parameters: atrial volume, transmitral Doppler peak A velocity, atrial fraction, and atrial ejection force.
- Exploration of newer echocardiographic techniques: Doppler tissue imaging (DTI), including segmental atrial function assessment, strain, and strain rate.
Main Results:
- Conventional methods provide insights into phasic atrial activity and function.
- Advanced DTI techniques offer detailed assessment of atrial mechanics, including segmental function, strain, and strain rate.
- An enlarged left atrium is associated with various clinical implications.
Conclusions:
- Echocardiography offers a range of parameters to evaluate left atrial size and function.
- Understanding these parameters is crucial for assessing cardiac and cerebrovascular risk.
- Further research is needed to fully elucidate the prognostic power of LA volume.
Abstract:
Left atrial (LA) volume has recently been identified as a potential biomarker for cardiac and cerebrovascular disease. However, evidence regarding the prognostic implications of LA volume still remains unclear. Evaluation of LA size and function using traditional and more recent echocardiographic parameters is potentially feasible in the routine clinical setting. This review article discusses the conventional and newer echocardiographic parameters used to evaluate LA size and function. Conventional parameters include the assessment of phasic atrial activity using atrial volume measurements, transmitral Doppler peak A velocity, atrial fraction, and the atrial ejection force. Newer parameters include Doppler tissue imaging (DTI) including segmental atrial function assessment using color DTI, strain, and strain rate. In addition, an overview of the implications and clinical relevance of the findings of an enlarged left atrium, from currently available literature, is presented.
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