Echocardiographic evaluation of left atrial size and function: current understanding, pathophysiologic correlates,

Dominic Y Leung1, Anita Boyd, Arnold A Ng

  • 1Liverpool Hospital, University of New South Wales, Sydney, New South Wales, Australia.

American Heart Journal
|November 27, 2008
PubMed

Insights

Left atrial (LA) volume is a potential biomarker for heart and cerebrovascular diseases. This review explores echocardiographic methods to assess LA size and function, clarifying its prognostic value.

Area of Science:

  • Cardiology
  • Echocardiography
  • Biomarkers

Background:

  • Left atrial (LA) volume is recognized as a potential biomarker for cardiovascular and cerebrovascular diseases.
  • The prognostic implications of LA volume require further clarification.
  • Assessing LA size and function via echocardiography is feasible in routine clinical practice.

Purpose of the Study:

  • To review conventional and novel echocardiographic parameters for evaluating LA size and function.
  • To discuss the clinical relevance and implications of an enlarged left atrium based on current literature.

Main Methods:

  • Discussion of conventional echocardiographic parameters: atrial volume, transmitral Doppler peak A velocity, atrial fraction, and atrial ejection force.
  • Exploration of newer echocardiographic techniques: Doppler tissue imaging (DTI), including segmental atrial function assessment, strain, and strain rate.

Main Results:

  • Conventional methods provide insights into phasic atrial activity and function.
  • Advanced DTI techniques offer detailed assessment of atrial mechanics, including segmental function, strain, and strain rate.
  • An enlarged left atrium is associated with various clinical implications.

Conclusions:

  • Echocardiography offers a range of parameters to evaluate left atrial size and function.
  • Understanding these parameters is crucial for assessing cardiac and cerebrovascular risk.
  • Further research is needed to fully elucidate the prognostic power of LA volume.

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