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Nasolacrimal Lavage as a Treatment for Ocular Surface Toxic Soup Syndrome
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Sweet syndrome presenting as resistant conjunctivitis.

Guillaume Michel1, Benoist Lhermitte, Bernard Cribier

  • 1Department of Ophthalmology, Strasbourg University Hospital, Louis Pasteur University, Strasbourg, France. g67michel@yahoo.fr

Cornea
|November 27, 2008
PubMed
Summary

This case report details a patient with chronic Sweet syndrome (SS) who developed severe bilateral chemosis. Ocular findings confirmed SS localization, highlighting a rare manifestation of this neutrophilic dermatosis.

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Area of Science:

  • Ophthalmology
  • Dermatology
  • Rheumatology

Background:

  • Sweet syndrome (SS) is a rare neutrophilic dermatosis typically affecting middle-aged women.
  • Anti-Tumor Necrosis Factor (TNF) therapy is used for chronic SS management.
  • Ocular manifestations of SS are uncommon.

Observation:

  • A patient with chronic SS undergoing anti-TNF therapy presented with severe bilateral chemosis.
  • Conjunctival biopsy was performed for diagnostic evaluation.

Findings:

  • Conjunctival biopsy confirmed ocular localization of Sweet syndrome.
  • This represents the first documented case of ocular SS with severe bilateral chemosis.

Implications:

  • This case expands the spectrum of ocular manifestations of Sweet syndrome.
  • Ophthalmologists and dermatologists should consider SS in patients presenting with unexplained chemosis.
  • Further research into the ocular involvement of SS is warranted.