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Plasmodium Falciparum infection transmitted by living kidney donation: a case report from Iran

Behzad Einollahi1

  • 1Nephrology Research Center, Baqiyatallah University of Medical Sciences. Tehran, Iran. behzad.einollahi@gmail.com

Annals of Transplantation
|November 27, 2008
PubMed
Abstract

Insights

A kidney transplant recipient contracted malaria from the donor, a rare but serious complication. Prompt antimalarial therapy led to full recovery, highlighting the importance of donor screening for malaria.

Area of Science:

  • Nephrology
  • Infectious Diseases
  • Transplantation Immunology

Background:

  • Malaria transmission via organ donation is a rare, life-threatening risk in kidney transplantation.
  • Donor-derived malaria poses a significant, albeit infrequent, threat to transplant recipients.

Observation:

  • A 28-year-old male recipient developed malaria 10 days post-kidney transplant.
  • The donor, a healthy laborer, was a long-term resident of a malarious region in southern Iran.

Findings:

  • The recipient presented with intravascular hemolysis, mild acute renal failure, and fever.
  • Blood film analysis confirmed Plasmodium falciparum infection, indicated by intraerythrocytic ring forms.

Implications:

  • This case underscores the necessity for rigorous donor screening to prevent malaria transmission in kidney transplant recipients.
  • Early diagnosis and prompt antimalarial treatment are crucial for favorable outcomes in post-transplant malaria.
  • This is the first reported instance of malaria transmission from a donor following kidney transplantation in Iran.

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