Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Bones of the Lower Limb: Tibia and Fibula

Bones of the Lower Limb: Tibia and Fibula

The tibia is the main weight-bearing bone of the lower leg. It is larger than the fibula with which it is paired. The tibia is also the second longest bone in the body and is located right below the skin. The proximal end of the tibia forms the medial and the lateral condyle, which articulates with the condyles of the femur to form the knee joint. Between the articulating surfaces is the irregular elevated area known as the intercondylar eminence that serves as the inferior attachment point for...

Bone Formation by Intramembranous Ossification

Bone Formation by Intramembranous Ossification

Intramembranous ossification is one of the two processes involved in the development of bones within an embryo. The flat bones of the face, most of the cranial bones, and the clavicles are formed via this process. During intramembranous ossification, the bones develop directly from sheets of undifferentiated mesenchymal connective tissue.
The process begins when mesenchymal cells in the embryonic skeleton gather together and differentiate into osteogenic cells, which then develop into...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Robotic-assisted ligament-guided unicompartmental knee arthroplasty for medial compartment osteoarthritis: Current concepts.

Journal of ISAKOS : joint disorders & orthopaedic sports medicine·2026

Same author

How accurate are arthroplasty surgeons in visually estimating extension and flexion gaps in total knee arthroplasty?

Bone & joint open·2026

Same author

HIPrevision - a multicenter prospective randomized control superiority trial of antimicrobial IP-coated revision hip prostheses versus non-IP-coated comparators for the revision of periprosthetic hip joint infections.

Trials·2026

Same author

Osteoarthritis Bone Marrow MSCs Retain Regenerative Competence and Chemokine Responsiveness for Drug-Based In Situ Tissue Engineering.

Stem cells international·2026

Same author

2025 ICM: Skin Preparation.

The Journal of arthroplasty·2025

Same author

Tobacco's toll: Comparable anterior cruciate ligament graft failure rates and inferior functional outcomes in smokers compared to non-smokers: A systematic review and meta-analysis.

Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA·2025

Search research articles

Related Experiment Video

Updated: Jun 27, 2026

Direct Mouse Trauma/Burn Model of Heterotopic Ossification

Direct Mouse Trauma/Burn Model of Heterotopic Ossification

Published on: August 6, 2015

Heterotopic ossification post navigated high tibial osteotomy.

Mustafa Citak¹, Daniel Kendoff, Padhraig F O'Loughlin

¹Orthopaedic Department, Hospital for Special Surgery, New York, NY, USA. mcitak@gmx.de

Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA

|November 27, 2008

Summary

Heterotopic ossification (HO) occurred after navigated high tibial osteotomy using invasive markers, requiring revision surgery. This highlights the need for non-invasive reference markers in orthopedic procedures.

Related Experiment Videos

Last Updated: Jun 27, 2026

Direct Mouse Trauma/Burn Model of Heterotopic Ossification

Direct Mouse Trauma/Burn Model of Heterotopic Ossification

Published on: August 6, 2015

Area of Science:

Orthopedic Surgery
Medical Technology

Background:

Navigated high tibial osteotomy is a common procedure for knee osteoarthritis.
Invasive reference markers are currently the standard for surgical navigation.

Observation:

A rare case of heterotopic ossification (HO) was observed following navigated high tibial osteotomy.
The HO necessitated a second surgical intervention.

Findings:

No prior literature reports HO associated with invasive navigation reference markers.
This case suggests a potential complication linked to invasive marker use.

Implications:

The findings emphasize the importance of considering non-invasive reference markers.
This could lead to improved patient safety and reduced complications in navigated orthopedic surgery.