Related Experiment Videos
Preparation of lyophilized heat-treated cryoprecipitates from a small pool of plasma obtained by apheresis
D P Allersma1, E Roeffen, J A Van der Does
1Central Pharmacy of the Hospitals of The Hague, The Netherlands.
Pharmaceutisch Weekblad. Scientific Edition
|February 22, 1991
Abstract:
A method was developed for the batch-wise production of small-pool lyophilized heat-treated cryoprecipitates in a regional Blood Bank. Ten vials of final product were derived from twenty 600 g apheresis plasma donations. We found 384 IU of factor VIII per vial and a specific activity of 0.20 IU per mg total protein. Production recovery was 340 IU of factor VIII per kg plasma. The method was easy to perform and gave a product of good quality.