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A phosphine-mediated conversion of azides into diazo compounds

Eddie L Myers1, Ronald T Raines

  • 1Department of Biochemistry, University of Wisconsin-Madison, 433 Babcock Drive, Madison, WI 53706, USA.

Angewandte Chemie (International Ed. in English)
|November 28, 2008
PubMed
Summary

A new mild method converts azides into diazo compounds using an acyl triazene intermediate, inspired by the Staudinger ligation. This approach is suitable for complex molecules with sensitive functional groups in organic synthesis.

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