Quick-brain magnetic resonance imaging for nonhydrocephalus indications

Area of Science:

• Pediatric Radiology
• Neuroimaging Techniques

Background:

• Quick-Brain (QB) MR imaging, an ultrafast spin echo T2-weighted technique, was initially developed as an alternative to CT for pediatric hydrocephalus assessment.
• High patient and physician satisfaction has driven the adoption of QB MR imaging for a wider range of non-hydrocephalic indications.

Purpose of the Study:

• To characterize and quantify the utilization of QB MR imaging for non-hydrocephalic pediatric indications.
• To assess the clinical experience and evolving role of QB MR imaging in various pediatric neurological conditions.

Main Methods:

• A retrospective review of 1146 consecutive QB MR imaging studies performed between February 2003 and December 2007.
• Indications were categorized, including hydrocephalus, macrocephaly, Chiari malformation, intracranial cysts, pre-lumbar puncture screening, congenital anomaly screening, trauma, and others.
• Analysis of changes in indication distribution over time and clinical experience for each indication.

Main Results:

• The total number of QB MR imaging studies increased annually, with a significant rise in non-hydrocephalic indications (from 23% to 50%).
• Screening for macrocephaly was the most frequent non-hydrocephalic indication; other indications were evenly distributed.
• QB MR imaging proved effective for initial evaluation and follow-up, often negating the need for additional imaging, though its false-negative rate is unknown.

Conclusions:

• The application of QB MR imaging for non-hydrocephalic pediatric conditions is expanding and shows potential for screening and surveillance.
• Development of "Quick-Brain plus" protocols tailored to specific indications may improve sensitivity and are currently under investigation.