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Published on: August 16, 2018
A new naturally acetylated triterpene saponin from Nigella sativa
Bhupendra Kumar Mehta1, Prabha Mehta, Meenal Gupta
1School of Studies in Chemistry and Biochemistry, Vikram University, Ujjain 456 010, M.P., India. bkmehta11@yahoo.com
Abstract:
A new glycosylated triterpene 1 was identified as 3-O-[beta-D-xylopyranosyl-(1-->3)-alpha-l-rhamnopyranosyl-(1-->4)-beta-D-glucopyranosyl]-11-methoxy-16-hydroxy-17-acetoxy hederagenin from an ethanolic extract of seeds of Nigella sativa Linn. Identification of the naturally acetylated saponin was based on chemical and spectroscopic analyses including FABMS, (1)H, (13)C, and 2D NMR and DEPT. The saponin was a penta hydroxy pentacyclic triterpene, in which one hydroxyl group was acetylated and other one was methylated naturally.
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