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Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
Published on: June 13, 2021
Common symptoms during pregnancy to predict depression and health status 14 years post partum
Mohsina Khatun1, Alexandra M Clavarino, Leonie Callaway
1Princess Alexandra Hospital, Brisbane, Australia.
Objective:
To examine the prospective association between symptoms commonly experienced during pregnancy and the mental and general health status of women 14 years post partum.
Methods:
Data used were from the Mater-University of Queensland Study of Pregnancy, a community-based prospective birth cohort study begun in Brisbane, Australia, in 1981. Logistic regression analyses were conducted.
Results:
Data were available for 5118 women. Women who experienced a higher burden of symptoms during pregnancy were at greater risk of becoming depressed and reporting poorer health status 14 years post partum. Women who experienced major problems during pregnancy were 4 times more likely to be depressed and nearly 8 times more likely to report poorer health status 14 years after the index pregnancy compared with women who experienced few problems.
Conclusions:
Findings suggest that pregnant women who experience common symptoms during pregnancy are likely to experience poorer mental and self-reported general health 14 years after the pregnancy.
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