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Obesity across the lifespan among persons with spina bifida
Nienke P Dosa1, John T Foley, Michael Eckrich
1Center for Development, Behavior, and Genetics, SUNY Upstate Medical University, Syracuse, NY 13210, USA. dosan@upstate.edu
Insights
Obesity is common in adults with spina bifida, especially women. Risk factors for obesity in spina bifida patients are similar to the general population, with lower functional motor levels increasing risk in adolescents.
Area of Science:
- Medical research
- Public health
- Pediatrics
Background:
- Spina bifida is a complex congenital condition impacting mobility and health.
- Obesity presents unique challenges for individuals with spina bifida across different age groups.
- Understanding lifespan risk factors is crucial for targeted interventions.
Purpose of the Study:
- To identify risk factors associated with obesity throughout the lifespan in individuals diagnosed with spina bifida.
- To compare obesity prevalence across pediatric, adolescent, and adult age groups with spina bifida.
Main Methods:
- A cross-sectional chart review of 203 spina bifida patients (ages 6-58).
- Obesity defined by body mass index (BMI) and categorized by age groups: children (6-11), adolescents (12-19), and adults (>20).
- Statistical analyses included chi-square tests and ordered logistic regression, controlling for sex, motor function, shunt status, and insurance.
Main Results:
- Obesity rates were 18% (children), 8% (adolescents), and 37% (adults).
- Adults and publicly insured individuals showed higher obesity rates.
- Adolescents with lower functional motor levels (sacral) had increased obesity risk (OR=2.13).
- Adult women had increased obesity risk (OR=2.28).
Conclusions:
- While childhood and adolescent obesity rates are comparable to the general population, adult obesity is significantly higher in spina bifida patients.
- Female sex and lower functional motor level are identified risk factors for obesity in adults and adolescents, respectively.
- Risk factors for obesity in spina bifida mirror those found in the general population.
Purpose:
Identify risk factors for obesity across the lifespan for individuals with spina bifida.
Methods:
Cross sectional chart review study of 203 patients aged 6-58 years. Obesity was based on body mass index. Rates were calculated for children aged 6-11 years; adolescents aged 12-19 years and adults aged > 20 years. Chi-square analyses were used to determine differences in obesity rates among subgroups. An ordered logistic regression model was developed for the three age groups to estimate the probability of a change in BMI classification from normal weight to overweight or overweight to obese, controlling for sex, functional motor level, shunt status and insurance status.
Results:
Obesity rates for children, adolescents and adults were 18, 8 and 37%, respectively. Obesity rates were higher among adults (chi2 = 27, p < 0.01) and for individuals who were publicly insured (chi2 = 7.2, p < 0.03). The ordered regression model for children demonstrated no independent association between sex, shunt status, functional motor level or insurance status and change in BMI category. For adolescents, lower functional motor level (i.e. sacral) increased the risk of becoming obese (Odds Ratio: 2.13; 95% CI: 1.12-4.06; p < 0.02). Among adults, female sex increased risk (OR = 2.28; 95% CI: 1.03-5.04; p < 0.04).
Conclusions:
Obesity rates for children and adolescents with spina bifida are similar to the general population; however, obesity rates are higher among adults, particularly women. Risk factors are similar to those observed in the general population.
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