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Related Experiment Video

Updated: Jun 27, 2026

Fingerprinting Cardiolipin in Leukocytes by Mass Spectrometry for a Rapid Diagnosis of Barth Syndrome

Fingerprinting Cardiolipin in Leukocytes by Mass Spectrometry for a Rapid Diagnosis of Barth Syndrome

Published on: March 23, 2022

Bertolotti's syndrome: a case report.

Raj Mitra¹, Mark Carlisle

¹Interventional Spine Center, Division of Physical Medicine & Rehabilitation, Stanford University School of Medicine, 300 Pasteur Dr., Edwards Bldg., Palo Alto, California 94305, USA. rrmitra@stanford.edu

Pain Practice : the Official Journal of World Institute of Pain

|November 29, 2008

Summary

Intra-articular steroid injections provided significant relief for a patient with Bertolotti's syndrome, suggesting a potential non-surgical treatment option for axial low back pain.

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Last Updated: Jun 27, 2026

Fingerprinting Cardiolipin in Leukocytes by Mass Spectrometry for a Rapid Diagnosis of Barth Syndrome

Fingerprinting Cardiolipin in Leukocytes by Mass Spectrometry for a Rapid Diagnosis of Barth Syndrome

Published on: March 23, 2022

Area of Science:

Pain management
Spine surgery
Rheumatology

Background:

Bertolotti's syndrome is a condition characterized by axial low back pain, often linked to arthritic changes.
The precise source of pain in Bertolotti's syndrome remains unclear.
The transverse process-ilium articulation is a potential, yet unconfirmed, pain generator.

Observation:

A case report details a patient experiencing symptomatic Bertolotti's syndrome.
The patient's axial low back pain was managed with intra-articular steroid injections.
The injections targeted the ilium-transverse process articulation.

Findings:

The patient achieved significant relief from axial pain following the steroid injection.
This suggests the transverse process-ilium articulation can be a pain generator in Bertolotti's syndrome.

Implications:

Intra-articular steroid injections may offer a viable non-surgical treatment alternative for Bertolotti's syndrome.
Further research is warranted to confirm the efficacy and long-term outcomes of this treatment approach.
This finding could guide future management strategies for patients with similar presentations of low back pain.