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Published on: March 21, 2013
Postural orthostatic tachycardia in a teenager with Klinefelter syndrome
Michael R Hainstock1, Nancy E Gruchala, Nadia Fike
1University of Arizona College of Medicine, Department of Pediatrics, Tucson, AZ, USA. hainstoc@ohsu.edu
Abstract:
To our knowledge this is the first reported case of postural orthostatic tachycardia syndrome (POTS) in a patient with Klinefelter syndrome. We describe a classic clinical presentation of POTS in an adolescent male with Klinefelter syndrome. Although the etiology of POTS appears to be multifactorial, there is a strong female predominance that suggests a genetic basis. Our patient with Klinefelter syndrome may further support a link with POTS to the X chromosome.
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