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Aspergillus genomes and the Aspergillus cloud
Jane E Mabey Gilsenan1, Graham Atherton, Jennifer Bartholomew
1School of Medicine, The University Hospital of South Manchester (Wythenshawe), Manchester M23 9LT, UK. jane.gilsenan@manchester.ac.uk
Nucleic Acids Research
|November 29, 2008
Summary
Aspergillus Genomes integrates medical and fungal genomic data, offering a unified resource for Aspergillus research. This public database enhances understanding of fungal pathogens and their clinical relevance.
Area of Science:
- Fungal Genomics
- Medical Mycology
- Bioinformatics
Background:
- Aspergillus species are significant fungal pathogens causing aspergillosis.
- Existing resources like the Aspergillus/Aspergillosis website and CADRE served distinct communities (medical vs. genomic).
- A need existed for a consolidated resource integrating genomic and clinical data for the Aspergillus genus.
Purpose of the Study:
- To create a unified public resource for annotated Aspergillus genes.
- To merge medical and genomic information for a comprehensive view of Aspergillus.
- To facilitate research spanning the genomics and clinical aspects of Aspergillus.
Main Methods:
- Union of the Aspergillus/Aspergillosis website and the Central Aspergillus Data REpository (CADRE).
- Integration of gene annotation data from various Aspergillus sequencing projects.
- Cross-linking of genomic information with medical data on Aspergillus and associated diseases.
Main Results:
- Establishment of Aspergillus Genomes as a comprehensive public resource.
- Extensive cross-linking between genomic data and clinical information.
- A unique resource is now available for researchers in both mycology and medicine.
Conclusions:
- The merged database provides a powerful, integrated platform for Aspergillus research.
- Aspergillus Genomes facilitates a deeper understanding of fungal pathogens from genomic to clinical perspectives.
- This resource supports advancements in the study and treatment of aspergillosis.
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