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Published on: April 24, 2020
Intraocular pressure in schizophrenic patients treated with psychiatric medications
Valéria Barreto Novais E Souza1, Francisco José Rodrigues de Moura Filho, Fábio Gomes de Matos E Souza
1Universidade Federal do Ceará, Fortaleza, CE, Brasil. valbns@yahoo.com.br
Purpose:
In order to assess the occurrence of adverse ocular effects of antipsychotic drugs, we sought to evaluate intraocular pressure of schizophrenic patients treated with psychiatric medications.
Methods:
Twenty-eight outpatients with DSM-IV diagnosis of schizophrenia who met both the inclusion and exclusion criteria were submitted to an ophthalmic evaluation for ocular abnormalities which included intraocular pressure measurement with Goldmann applanation tonometry.
Results:
Raised intraocular pressure was found in three patients (11%). Abnormality in cup-disc ratio was seen in only one patient with cup-disc ratio asymmetry of 0.4. All these four patients were taking only ziprasidone.
Conclusions:
Patients using ziprasidone were found to have abnormalities in both intraocular pressure and cup-disc ratio.
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