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Updated: Jun 27, 2026

Occlusion of the Great and Small Saphenous Vein Using Copolymeric Glue Based on N-Butyl Cyanoacrylate and Methacryloxy Sulfolane
Published on: December 9, 2022
Venous leg ulcers--a surgical treatment
11st Department of Surgery, University Hospital Bratislava, Faculty of Medicine, Comenius University, Bratislava, Slovakia. mcambal@zoznam.sk
Compression sclerotherapy is the most effective treatment for venous ulcers. For persistent cases unresponsive to other methods, surgical valve repair may be considered.
Area of Science:
- Vascular Surgery
- Phlebology
Background:
- Venous ulcers represent a significant challenge in vascular surgery.
- Effective treatment requires addressing reflux at all venous system levels.
Purpose of the Study:
- To evaluate complex anti-reflux treatments for venous ulcers.
- To compare therapeutic outcomes across different treatment modalities.
Main Methods:
- Analysis of 793 patients over 20 years.
- Comparison of surgical (Linton+vein surgery) vs. sclerotherapy (Fegan's technique) combined with anti-reflux surgery.
- Focus on refractory ulcers unresponsive to superficial and perforator therapy.
Main Results:
- Compression sclerotherapy (Fegan's technique) demonstrated high efficacy.
- Direct valve repair is suitable for rare non-thrombotic deep vein reflux (0.6%).
- In situ valve construction may benefit patients with refractory ulcers (4.6%) where sclerotherapy failed.
Conclusions:
- Compression sclerotherapy is the preferred method for venous ulcers.
- Surgical interventions are reserved for specific, rare cases of deep vein reflux.
- Novel valve reconstruction techniques offer potential for treatment-resistant venous ulcers.
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