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Personalizing nutrigenomics research through community based participatory research and omics technologies
Beverly McCabe-Sellers1, Dalia Lovera, Henry Nuss
1USDA-ARS Delta NIRI. 900 South Shackleford Drive, Little Rock, AR 72211, USA.
Omics : a Journal of Integrative Biology
|December 2, 2008
Summary
Personalized nutrition and medicine require new research strategies. Community-based participatory research (CBPR) offers a promising approach for in-depth lifestyle analysis and improved community health.
Area of Science:
- Nutrigenomics and Personalized Medicine
- Community-Based Participatory Research (CBPR)
Background:
- Population studies provide risk factors for nutrients, toxins, and gene variants, but individual applicability is limited.
- Current intervention studies face limitations in sample size, duration, and design variability, hindering personalized analysis.
- Nutrigenomics faces a challenge in developing individual-specific metabolic risk factors.
Purpose of the Study:
- To explore new experimental strategies for human study designs to achieve personalized medicine and nutrition.
- To investigate the potential of community-based participatory research (CBPR) for analyzing genetic and environmental interactions.
- To highlight the role of CBPR in advancing personalized nutrition and medicine research.
Main Methods:
- Utilizing community-based participatory research (CBPR) methodologies to foster partnerships between researchers and communities.
- Conducting in-depth lifestyle analyses through community-researcher collaborations.
- Implementing translational research within communities to improve health outcomes.
Main Results:
- CBPR enables more comprehensive analyses of genetic makeup and environmental interactions.
- Partnerships facilitate deeper lifestyle assessments and simultaneous health improvements for individuals and communities.
- The USDA-ARS Delta Nutrition Intervention Research program serves as a model for CBPR in personalized nutrition.
Conclusions:
- CBPR methodologies are essential for developing personalized nutrition and medicine.
- Translational research through CBPR can effectively improve community and individual health.
- Expanded personalized nutrition and medicine research is facilitated by CBPR approaches, as exemplified by the USDA-ARS program.
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