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Published on: June 5, 2020
Erythema nodosum migrans in a male patient with hepatitis B infection
E Lazaridou1, Z Apalla, A Patsatsi
1First Department of Dermatology-Venereology, Aristotle University Medical School, Thessaloniki, Greece. bethlaz@med.auth.gr
Abstract:
Erythema nodosum migrans (ENM) is believed to represent a variant of chronic erythema nodosum; however, others consider it to be a separate clinical entity. It most commonly affects women in the third to sixth decade of life. Most cases are idiopathic, but some may be associated with streptococcal infection or thyroid disease. We present a case of ENM in a 33-year-old male patient with an erythematous, painful and infiltrated nodule on the lateral left lower leg. The lesion enlarged centrifugally, and a similar lesion appeared on the right lower leg. Both plaques exhibited a tendency to central clearing that made a peripheral ring evident. The patient was concurrently under treatment with antiviral drugs for hepatitis B infection and had an excellent response to treatment with potassium iodide. An association of ENM with the patient's viral hepatitis B could not be excluded.
Insights
Erythema nodosum migrans (ENM), a skin condition, can occur in men and may be linked to Hepatitis B infection. Treatment with potassium iodide showed positive results in this case.
Area of Science:
- Dermatology
- Infectious Diseases
Background:
- Erythema nodosum migrans (ENM) is debated as a variant of chronic erythema nodosum or a distinct entity.
- Typically affects women aged 30-60; often idiopathic but can link to streptococcal infection or thyroid disease.
Observation:
- A 33-year-old male presented with painful, infiltrated leg nodules characteristic of ENM.
- Lesions spread centrifugally with central clearing, forming annular plaques.
- The patient had concurrent Hepatitis B infection treated with antivirals.
Findings:
- The case presented an unusual occurrence of ENM in a male patient.
- Potassium iodide treatment yielded an excellent response.
- A potential association between ENM and Hepatitis B infection was noted.
Implications:
- This case expands the known demographic of ENM, including males.
- Suggests a possible link between viral hepatitis and ENM development.
- Highlights potassium iodide as a potential treatment option for ENM.
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