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Hollow spherical nanostructured polydiphenylamine for direct electrochemistry and glucose biosensor
P Santhosh1, K M Manesh, S Uthayakumar
1Department of Chemistry Graduate School, Kyungpook National University, Daegu 702-701, South Korea.
Abstract:
Nanostructured, hollow spheres of polydiphenylamine (HS-PDPA) are prepared through a "soft template assisted self-assembly" approach. An enzymatic glucose biosensor is fabricated through immobilizing glucose oxidase (GOx) into HS-PDPA matrix. The HS-PDPA-GOx electrode exhibits a pair of well-defined reversible redox peaks with a fast heterogeneous electron transfer rate. At an applied potential of +0.65V, HS-PDPA-GOx electrode possesses high sensitivity (1.77 microAmM(-1)cm(-2)), stability and reproducibility towards glucose. The amperometric current response of HS-PDPA-GOx to glucose is linear in the concentration range between 1 and 28 mM with a detection limit of 0.05 mM (S/N=3). Also, HS-PDPA-GOx electrode shows high selectivity towards glucose in the presence of ascorbic acid, uric acid and acetaminophen at their maximum physiological concentrations.
